Reaction: Telotristat ethyl to 1 product

Reaction
Telotristat ethyl
DB12095
Telotristat
DBMET03552
Reaction type
O-deethylation
Direction
Major circulating metabolite?
Yes
Spontaneous?
No
Activity
active
References
  1. FDA Approved Drug Products: XERMELO® (telotristat ethyl) tablets, for oral use 2022 [Link]
  2. CLINICAL PHARMACOLOGY AND BIOPHARMACEUTICS REVIEW(S) [Link]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Liver carboxylesterase 1Not AvailableNot Availableconfirmed
Cocaine esteraseNot AvailableNot Availableconfirmed