Pseudoephedrine hydrochlorideProduct ingredient for Pseudoephedrine
- Name
- Pseudoephedrine hydrochloride
- Drug Entry
- Pseudoephedrine
Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.1,2 Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889.2 The decongestant effect of pseudoephedrine was described in dogs in 1927.2
- Accession Number
- DBSALT000149
- Structure
Structure for Pseudoephedrine hydrochloride (DBSALT000149)
- Synonyms
- Pseudoephedrine HCl
- UNII
- 6V9V2RYJ8N
- CAS Number
- 345-78-8
- Weight
- Average: 201.693
Monoisotopic: 201.092041846 - Chemical Formula
- C10H16ClNO
- InChI Key
- BALXUFOVQVENIU-KXNXZCPBSA-N
- InChI
- InChI=1S/C10H15NO.ClH/c1-8(11-2)10(12)9-6-4-3-5-7-9;/h3-8,10-12H,1-2H3;1H/t8-,10+;/m0./s1
- IUPAC Name
- (1S,2S)-2-(methylamino)-1-phenylpropan-1-ol hydrochloride
- SMILES
- Cl.CN[C@@H](C)[C@@H](O)C1=CC=CC=C1
- External Links
- PubChem Compound
- 9581
- ChemSpider
- 9205
- ChEBI
- 8604
- ChEMBL
- CHEMBL1200724
- Wikipedia
- Pseudoephedrine
- Predicted Properties
Property Value Source Water Solubility 8.26 mg/mL ALOGPS logP 1 ALOGPS logP 1.32 Chemaxon logS -1.3 ALOGPS pKa (Strongest Acidic) 13.89 Chemaxon pKa (Strongest Basic) 9.52 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 32.26 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 49.69 m3·mol-1 Chemaxon Polarizability 18.76 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon