Olsalazine sodiumProduct ingredient for Olsalazine

Olsalazine is an aminosalicylate and a prodrug of mesalamine (5-aminosalicylic acid, 5-ASA).¹ It was first developed for delivering mesalamine to the colon without the use of sulfapyridine.² Olsalazine comprises two mesalamine molecules joined by an azo bridge, which is cleaved in the colon.² Olsalazine is an anti-inflammatory agent that works by inhibiting cyclooxygenase and lipoxygenase, subsequently reducing the production of pro-inflammatory factors like prostaglandin and leukotriene.¹ Olsalazine is used in the treatment of ulcerative colitis.^5,6