Cinchocaine hydrochlorideProduct ingredient for Cinchocaine
- Name
- Cinchocaine hydrochloride
- Drug Entry
- Cinchocaine
A local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)
- Accession Number
- DBSALT000639 (DBSALT001401)
- Structure
Structure for Cinchocaine hydrochloride (DBSALT000639)
- Synonyms
- Cinchocaine HCl / Dibucaine HCl / Dibucaine hydrochloride
- UNII
- Z97702A5DG
- CAS Number
- 61-12-1
- Weight
- Average: 379.924
Monoisotopic: 379.202654926 - Chemical Formula
- C20H30ClN3O2
- InChI Key
- IVHBBMHQKZBJEU-UHFFFAOYSA-N
- InChI
- InChI=1S/C20H29N3O2.ClH/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3;/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24);1H
- IUPAC Name
- 2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide hydrochloride
- SMILES
- Cl.CCCCOC1=NC2=CC=CC=C2C(=C1)C(=O)NCCN(CC)CC
- External Links
- PubChem Compound
- 6078
- ChemSpider
- 5853
- ChEBI
- 59735
- ChEMBL
- CHEMBL1200612
- Wikipedia
- Cinchocaine
- Predicted Properties
Property Value Source Water Solubility 0.0389 mg/mL ALOGPS logP 3.79 ALOGPS logP 3.7 Chemaxon logS -4 ALOGPS pKa (Strongest Acidic) 14.57 Chemaxon pKa (Strongest Basic) 9.04 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 54.46 Å2 Chemaxon Rotatable Bond Count 10 Chemaxon Refractivity 102.12 m3·mol-1 Chemaxon Polarizability 40.78 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon