Minocycline hydrochlorideProduct ingredient for Minocycline

Minocycline was first described in the literacture in 1966.¹ It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria.⁷ Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines.⁷

Minocycline was granted FDA approval on 30 June 1971.⁹