Guanidine hydrochlorideProduct ingredient for Guanidine
- Name
- Guanidine hydrochloride
- Drug Entry
- Guanidine
A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
- Accession Number
- DBSALT000737
- Structure
Structure for Guanidine hydrochloride (DBSALT000737)
- Synonyms
- Guanidine HCl
- UNII
- 3YQC9ZY4YB
- CAS Number
- 50-01-1
- Weight
- Average: 95.531
Monoisotopic: 95.025024914 - Chemical Formula
- CH6ClN3
- InChI Key
- PJJJBBJSCAKJQF-UHFFFAOYSA-N
- InChI
- InChI=1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H
- IUPAC Name
- guanidine hydrochloride
- SMILES
- Cl.NC(N)=N
- External Links
- PubChem Compound
- 5742
- ChemSpider
- 5540
- ChEBI
- 32735
- ChEMBL
- CHEMBL1200728
- Wikipedia
- Guanidinium_chloride
- Predicted Properties
Property Value Source Water Solubility 11.5 mg/mL ALOGPS logP -1.9 ALOGPS logP -1.2 Chemaxon logS -0.71 ALOGPS pKa (Strongest Basic) 12.55 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 3 Chemaxon Polar Surface Area 75.89 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 25.86 m3·mol-1 Chemaxon Polarizability 5.57 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon