Metoprolol succinateProduct ingredient for Metoprolol

Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.^2,9 The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative.⁵ To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US.³ Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.⁸