Propoxycaine hydrochlorideProduct ingredient for Propoxycaine

Show full entry for Propoxycaine
Name
Propoxycaine hydrochloride
Drug Entry
Propoxycaine

Propoxycaine is a local anesthetic of the ester type that has a rapid onset of action and a longer duration of action than procaine hydrochloride 3. This drug was removed from the US market in 1996. Although no longer available in the United States, this medication was used in combination with procaine to aid in anesthesia during dental procedures 5. Used in combination with procaine, it was the only dental local anesthetic available in cartridge form 5.

See full entry for Propoxycaine
Accession Number
DBSALT001348
Structure
Similar Structures
Synonyms
Propoxycaine HCl
UNII
K490D39G46
CAS Number
550-83-4
Weight
Average: 330.85
Monoisotopic: 330.1710204
Chemical Formula
C16H27ClN2O3
InChI Key
GITPCGSPKUQZTE-UHFFFAOYSA-N
InChI
InChI=1S/C16H26N2O3.ClH/c1-4-10-20-15-12-13(17)7-8-14(15)16(19)21-11-9-18(5-2)6-3;/h7-8,12H,4-6,9-11,17H2,1-3H3;1H
IUPAC Name
2-(diethylamino)ethyl 4-amino-2-propoxybenzoate hydrochloride
SMILES
Cl.CCCOC1=C(C=CC(N)=C1)C(=O)OCCN(CC)CC
ChemSpider
10607
ChEMBL
CHEMBL1769
Wikipedia
Propoxycaine
Predicted Properties
PropertyValueSource
Water Solubility1.79 mg/mLALOGPS
logP2.89ALOGPS
logP2.6Chemaxon
logS-2.2ALOGPS
pKa (Strongest Basic)8.96Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count4Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area64.79 Å2Chemaxon
Rotatable Bond Count10Chemaxon
Refractivity86.04 m3·mol-1Chemaxon
Polarizability34.29 Å3Chemaxon
Number of Rings1Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon