Pheniramine maleateProduct ingredient for Pheniramine
- Name
- Pheniramine maleate
- Drug Entry
- Pheniramine
Pheniramine is a first-generation antihistamine in the alkylamine class, similar to brompheniramine and chlorpheniramine.3 It is used in some over-the-counter allergy as well as cold & flu products in combination with other drugs. Pheniramine's use as an anti-allergy medication has largely been supplanted by second-generation antihistamines such as cetirizine and loratadine.
- Accession Number
- DBSALT001440
- Structure
Structure for Pheniramine maleate (DBSALT001440)
- Synonyms
- Not Available
- UNII
- NYW905655B
- CAS Number
- 132-20-7
- Weight
- Average: 356.422
Monoisotopic: 356.173607261 - Chemical Formula
- C20H24N2O4
- InChI Key
- SSOXZAQUVINQSA-BTJKTKAUSA-N
- InChI
- InChI=1S/C16H20N2.C4H4O4/c1-18(2)13-11-15(14-8-4-3-5-9-14)16-10-6-7-12-17-16;5-3(6)1-2-4(7)8/h3-10,12,15H,11,13H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
- IUPAC Name
- (2Z)-but-2-enedioic acid; dimethyl[3-phenyl-3-(pyridin-2-yl)propyl]amine
- SMILES
- [H]\C(=C(/[H])C(O)=O)C(O)=O.CN(C)CCC(C1=CC=CC=C1)C1=CC=CC=N1
- External Links
- KEGG Compound
- C12574
- ChemSpider
- 4445339
- ChEBI
- 31990
- ChEMBL
- CHEMBL1653
- Wikipedia
- Pheniramine
- Predicted Properties
Property Value Source Water Solubility 0.377 mg/mL ALOGPS logP 2.85 ALOGPS logP 2.98 Chemaxon logS -2.8 ALOGPS pKa (Strongest Basic) 9.48 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 16.13 Å2 Chemaxon Rotatable Bond Count 7 Chemaxon Refractivity 76.05 m3·mol-1 Chemaxon Polarizability 28.38 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon