Tyramine hydrochlorideProduct ingredient for Tyramine
- Name
- Tyramine hydrochloride
- Drug Entry
- Tyramine
Tyramine (4-hydroxyphenethylamine; para-tyramine, mydrial or uteramin) is a naturally occurring monoamine compound and trace amine derived from the amino acid tyrosine. Tyramine acts by inducing the release of catecholamine. An important characteristic of this product is its impediment to cross the blood-brain barrier which restrains its side effects to only nonpsychoactive peripheral sympathomimetic effects. There have been reports of hypertensive crisis in patients ingesting tyramine-rich diet in conjunction with monoamine oxidase inhibitors (MAOIs).
- Accession Number
- DBSALT002213
- Structure
Structure for Tyramine hydrochloride (DBSALT002213)
- Synonyms
- Not Available
- UNII
- Z5KDH3H147
- CAS Number
- 60-19-5
- Weight
- Average: 173.64
Monoisotopic: 173.060741718 - Chemical Formula
- C8H12ClNO
- InChI Key
- RNISDHSYKZAWOK-UHFFFAOYSA-N
- InChI
- InChI=1S/C8H11NO.ClH/c9-6-5-7-1-3-8(10)4-2-7;/h1-4,10H,5-6,9H2;1H
- IUPAC Name
- 4-(2-aminoethyl)phenol hydrochloride
- SMILES
- Cl.NCCC1=CC=C(O)C=C1
- External Links
- ChemSpider
- 59821
- ChEMBL
- CHEMBL1255790
- Predicted Properties
Property Value Source Water Solubility 5.72 mg/mL ALOGPS logP -0.14 ALOGPS logP 0.68 Chemaxon logS -1.4 ALOGPS pKa (Strongest Acidic) 10.41 Chemaxon pKa (Strongest Basic) 9.66 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 46.25 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 41.27 m3·mol-1 Chemaxon Polarizability 15.33 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon