- Sodium selenite pentahydrate
- Drug Entry
- Selenious acid
Selenious acid is the acid form of sodium selenite, a form of selenium 8.
Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties. Selenium is a component of glutathione peroxidase enzyme, which protects cell components from oxidative damage due to peroxides produced during cellular metabolism 13.
Selenium (Se) has been demonstrated to prevent cancer in numerous animal models when administered selenium at levels exceeding the nutritional requirements. One study showed efficacy in the prevention of malignancy while utilizing a selenium supplement in humans. The reports from such studies have heightened the interest in additional human selenium supplementation studies to validate the results in larger populations 15.
Interestingly, selenium is being studied as a potential therapy in the prevention or management of atherosclerosis 18.
- Accession Number
- Selenious acid, disodium salt, pentahydrate
- CAS Number
- Average: 263.023
- Chemical Formula
- InChI Key
- IUPAC Name
- disodium pentahydrate selenite
- Predicted Properties
Property Value Source logP -1.3 ChemAxon pKa (Strongest Acidic) 1.2 ChemAxon Physiological Charge -2 ChemAxon Hydrogen Acceptor Count 4 ChemAxon Hydrogen Donor Count 0 ChemAxon Polar Surface Area 63.19 Å2 ChemAxon Rotatable Bond Count 0 ChemAxon Refractivity 17.44 m3·mol-1 ChemAxon Polarizability 5.32 Å3 ChemAxon Number of Rings 0 ChemAxon Bioavailability 1 ChemAxon Rule of Five Yes ChemAxon Ghose Filter No ChemAxon Veber's Rule No ChemAxon MDDR-like Rule No ChemAxon