Elamipretide hydrochlorideProduct ingredient for Elamipretide

Elamipretide is a mitochondrial cardiolipin binder being investigated for diseases involving mitochondrial dysfunction.⁵ Elamipretide is a synthetic tetrapeptide that selectively binds to cardiolipin, a phospholipid in the inner mitochondrial membrane.¹ This interaction improves mitochondrial morphology and function.⁶ In September 2025, the U.S. Food and Drug Administration (FDA) granted accelerated approval for FORZINITY™ (elamipretide) to improve muscle strength in adult and pediatric patients with Barth syndrome weighing at least 30 kg.⁶