Pilocarpine pamoateProduct ingredient for Pilocarpine
- Name
- Pilocarpine pamoate
- Drug Entry
- Pilocarpine
A naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist.1,2 Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors.2 Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated intraocular pressure and glaucoma. The usage of glaucoma by pilocarpine dates back to 1875.3
- Accession Number
- DBSALT003476
- Structure
Structure for Pilocarpine pamoate (DBSALT003476)
- Synonyms
- 2-NAPHTHALENECARBOXYLIC ACID, 4,4'-METHYLENEBIS(3-HYDROXY-, COMPD. WITH (3S-CIS)-3-ETHYLDIHYDRO-4((1-METHYL-1H-IMIDAZOL-5-YL)METHYL)-2(3H)-FURANONE (1:2) / DIPILOCARPINE PAMOATE
- UNII
- 9O3667EIIX
- CAS Number
- 63036-94-2
- Weight
- Average: 804.897
Monoisotopic: 804.337043762 - Chemical Formula
- C45H48N4O10
- InChI Key
- ZCECPEINCZVBPT-IWXKTIJTSA-N
- InChI
- InChI=1S/C23H16O6.2C11H16N2O2/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;2*1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2*5,7-8,10H,3-4,6H2,1-2H3/t;2*8-,10-/m.00/s1
- IUPAC Name
- bis((3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]oxolan-2-one); 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid
- SMILES
- CC[C@H]1[C@@H](CC2=CN=CN2C)COC1=O.CC[C@H]1[C@@H](CC2=CN=CN2C)COC1=O.OC(=O)C1=CC2=C(C=CC=C2)C(CC2=C3C=CC=CC3=CC(C(O)=O)=C2O)=C1O
- External Links
- ChemSpider
- 4956816
- Predicted Properties
Property Value Source logP 6.05 Chemaxon pKa (Strongest Acidic) 2.38 Chemaxon pKa (Strongest Basic) -6.2 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 115.06 Å2 Chemaxon Rotatable Bond Count 10 Chemaxon Refractivity 107.17 m3·mol-1 Chemaxon Polarizability 38.83 Å3 Chemaxon Number of Rings 8 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon