Protirelin tartrate monohydrateProduct ingredient for Protirelin
- Name
- Protirelin tartrate monohydrate
- Drug Entry
- Protirelin
Protirelin is the pharmaceutically available synthetic analogue of the endogenous peptide thyrotropin-releasing hormone (TRH). It is a tri-peptide tropic hormone, released by the hypothalamus, that stimulates the release of Thyroid Stimulating Hormone (TSH) and prolactin from the anterior pituitary.
Although not currently available in any FDA-approved product, protirelin is a component of the TRH Test where it is used to test the response of the anterior pituitary gland in conditions such as secondary hypothyroidism and acromegaly.
- Accession Number
- DBSALT003552
- Structure
Structure for Protirelin tartrate monohydrate (DBSALT003552)
- Synonyms
- L-PROLINAMIDE, 5-OXO-L-PROLYL-L-HISTIDYL-, (2R,3R)-2,3-DIHYDROXYBUTANEDIOATE (1:1), MONOHYDRATE / L-PROLINAMIDE, 5-OXO-L-PROLYL-L-HISTIDYL-, (R-(R*,R*))-2,3-DIHYDROXYBUTANEDIOATE (1:1), MONOHYDRATE / Protirelin tartrate monohydrate
- UNII
- 1N3H4TJE79
- CAS Number
- 56267-12-0
- Weight
- Average: 530.491
Monoisotopic: 530.19725581 - Chemical Formula
- C20H30N6O11
- InChI Key
- IMEQDWQCFHIYJB-LOMBACLASA-N
- InChI
- InChI=1S/C16H22N6O4.C4H6O6.H2O/c17-14(24)12-2-1-5-22(12)16(26)11(6-9-7-18-8-19-9)21-15(25)10-3-4-13(23)20-10;5-1(3(7)8)2(6)4(9)10;/h7-8,10-12H,1-6H2,(H2,17,24)(H,18,19)(H,20,23)(H,21,25);1-2,5-6H,(H,7,8)(H,9,10);1H2/t10-,11-,12-;1-,2-;/m01./s1
- IUPAC Name
- SMILES
- O.O[C@H]([C@@H](O)C(O)=O)C(O)=O.NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC1=CN=CN1)NC(=O)[C@@H]1CCC(=O)N1
- External Links
- Not Available
- Predicted Properties
Property Value Source