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Rivaroxaban
go.drugbank.com/drugs/DB06228ApprovedInvestigationalRivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. … However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food.
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: Ag-rivaroxaban, Ixobran 15 (Rivaroxaban Tablet Ph Eur 15mg)Valproic acid
go.drugbank.com/drugs/DB00313ApprovedInvestigational[A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. … a similar degree of anticonvulsive activity.
Categories: Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic IndexProducts: VALPRO AL 300MG RETARDTABL, VALPRO AL 500MG RETARDTABLProcaine
go.drugbank.com/drugs/DB00721ApprovedInvestigationalVet approvedA local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. … Procaine has also been investigated as an oral entry inhibitor in treatment-experienced HIV patients [L1215].
Synonyms: 2-Diethylaminoethyl p-aminobenzoate, β-(diethylamino)ethyl p-aminobenzoateProducts: SATYA®AL 1%, PROCAINA AL 1%Pravastatin
go.drugbank.com/drugs/DB00175ApprovedInvestigationalIt was the first statin administered as the active form and not as a prodrug.[T274] This drug was developed by Sankyo Co. … [L6142] Pravastatin is made through a fermentation process in which [mevastatin] is first obtained.
Categories: P-glycoprotein substratesProducts: Ag-pravastatin, Ava-pravastatinAluminum sulfate
go.drugbank.com/drugs/DB11239ApprovedIt is a chemical agent used in water purification, the pH regulation of garden soil, and other commercial or industrial applications. … Medically, it is primarily used as a coagulating agent in minor cuts and abrasions as well as deodorant [L2144].
Products: Sil Trax As No 8, Sil Trax As No 10Cyclobenzaprine
go.drugbank.com/drugs/DB00924ApprovedInvestigational[A184982] It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from [Amitriptyline] by only a single double bond. … [A185039,A184982] Since its approval, it has remained relatively popular as an adjunctive, short-term treatment for acute skeletal muscle spasms secondary to musculoskeletal injury.
Synonyms: (3-Dibenzo[a,d]cyclohepten-5-ylidene-propyl)-dimethyl-amine, N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-Δ5,γ-propylamineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesRizatriptan
go.drugbank.com/drugs/DB00953ApprovedInvestigationalRizatriptan is a second-generation triptan [A258918] and a selective 5-HT<sub>1B and 5-HT1D</sub> receptor agonist.
Categories: Monoamine Oxidase A Substrates, Cytochrome P-450 CYP2D6 InhibitorsProducts: Ag-rizatriptan ODT, RIZATRIPTAN AL 5MG TABLDermatophagoides farinae
go.drugbank.com/drugs/DB10400ApprovedInvestigationalThis combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.
Mixtures: Allergenic Extract Mixture Of Standardized Mites (5,000 Au/ml), Allergenic Extract Mixture Of Standardized Mites (15,000 Au/ml)Products: Allergenic Extract Standardized Mite Df (10,000 Au/ml), Allergenic Extract Standardized Mite Df (30,000 Au/ml)Dermatophagoides pteronyssinus
go.drugbank.com/drugs/DB10401ApprovedInvestigationalThis combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.
Mixtures: Allergenic Extract Mixture Of Standardized Mites (5,000 Au/ml), Allergenic Extract Mixture Of Standardized Mites (15,000 Au/ml)Synonyms: AE-mite, dermatophagoides pteronyssinusMeperidine
go.drugbank.com/drugs/DB00454ApprovedInvestigationalA narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: Pethidine HCl Fresenius PF 50mg/ml Injection, Demerol 50 mg/ml (multiple Dose With Metacresol As Preservative)