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Displaying results 91 - 100 of 10000 in total
  1. Drug

    Bremelanotide

    go.drugbank.com/drugs/DB11653
    Approved

    Bremelanotide is a 7 amino acid peptide used to treat hypoactive sexual desire disorder in premenopausal women.[L9635] Bremelanotide does not interact with alcohol. … [A179686] The mechanism by which bremelanotide's action on receptors translates to a clinical effect is still unknown.

    Categories: Receptor, Melanocortin, Type 3, agonists, Receptor, Melanocortin, Type 4, agonists
  2. Drug

    Lepirudin

    go.drugbank.com/drugs/DB00001
    ApprovedWithdrawn

    (N-terminal end). … Lepirudin is a recombinant hirudin formed by 65 amino acids that acts as a highly specific and direct thrombin inhibitor.

    Synonyms: R-hirudin, Hirudin variant-1
  3. Pathway

    Kidney Function- Proximal Convoluted Tubule

    smpdb.ca/view/SMP0121001
    Physiological

    The proximal convoluted tubule is part of the nephron between the Bowman's capsule and the loop of Henle. The proximal convoluted tubule functions to reabsorb sodium, water, and other ions. Sodium and bicarbonate (hydrogen carbonate) are...

    Drugs: Cysteine · Potassium cation · Zinc · Urea
    Enzymes: B(0,+)-type amino acid transporter 1
  4. Drug

    Apadamtase alfa

    go.drugbank.com/drugs/DB15164
    ApprovedInvestigational

    [A262076] Patients with cTTP have a severe deficiency of a plasma metalloproteinase called ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13), which is responsible … [A262076] It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP.

    Synonyms: Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs
  5. Drug

    Iptacopan

    go.drugbank.com/drugs/DB16200
    ApprovedInvestigational

    B. … Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor

    Categories: Complement Factor B Inhibitor, Cytochrome P-450 SubstratesSynonyms: 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl) benzoic acid, BENZOIC ACID, 4-((2S,4S)-4-ETHOXY-1-((5-METHOXY-7-METHYL-1H-INDOL-4-YL)METHYL)-2-PIPERIDINYL)-
  6. Drug

    Cefroxadine

    go.drugbank.com/drugs/DB11367
    ApprovedWithdrawn

    Cefroxadine is an orally available cephalosporin antibiotic. As part of its drug class, it shares structural properties to cefalexin as well as its activity spectrum. It was used in Italy but has since been withdrawn.

    Categories: Heterocyclic Compounds, 2-Ring
  7. Drug

    Vitamin D

    go.drugbank.com/drugs/DB11094
    ApprovedInvestigationalNutraceuticalVet approved

    Vitamin D3 and D2 require hydroxylation in order to become biologically active in the human body. … Since vitamin D can be endogenously synthesized in adequate amounts by most mammals exposed to sufficient quantities of sunlight, vitamin D functions like a hormone on vitamin D receptors to regulate calcium

    Synonyms: D Vitamin, Vitamin DMixtures: MULTI-TABS VITAMIN ACD DROPS 0-1 YAS ICIN ORAL DAMLA, 30 ML, Vitamin E Cream W Vitamins A and D
  8. Drug

    Damoctocog alfa pegol

    go.drugbank.com/drugs/DB14700
    ApprovedInvestigational

    in patients diagnosed with Haemophilia A. … In order to extend half-lives, techniques such as fusion to protein conjugates (Fc part of IgG1 or albumin), chemical modification (PEGylation), and protein sequence modification have been utilized.

  9. Drug

    Carbinoxamine

    go.drugbank.com/drugs/DB00748
    Approved

    The product label for carbinoxamine as an over the counter cough and cold medicine is being modified to state "do not use" in children under 4 years of age in order to prevent and reduce misuse, as many … Carbinoxamine is a first generation antihistamine that competes with free histamine for binding at HA-receptor sites.

    Synonyms: 2-(p-chloro-α-(2-(dimethylamino)ethoxy)benzyl)pyridine, {2-[(4-Chloro-phenyl)-pyridin-2-yl-methoxy]-ethyl}-dimethyl-amineMixtures: PHILDEX 2, RHINOPRONT UZUN ETKILI KAPSUL, 10 ADET
  10. Drug

    Galcanezumab

    go.drugbank.com/drugs/DB14042
    ApprovedInvestigational

    A pregnancy exposure registry has been established to evaluate the safety of this drug in pregnant women.[L42060] … Galcanezumab is a humanized monoclonal antibody developed by Eli Lilly and Company against human calcitonin gene-related peptide (CGRP).

    Products: EMGALİTY 120 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET, EMGALİTY 120 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 3 ADET