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Acyclovir
go.drugbank.com/drugs/DB00787ApprovedInvestigationalAcyclovir is a deoxynucleoside analog antiviral used to treat herpes simplex, Varicella zoster, herpes zoster, herpes labialis, and acute herpetic keratitis. Acyclovir is generally used first line in the treatment of these viruses and so...
Mixtures: VIROBIS LCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesNadroparin
go.drugbank.com/drugs/DB08813ApprovedInvestigationalWithdrawnNadroparin halts the coagulation pathway by inhibiting the activation of thrombin (factor IIa) by factor Xa. … Nadroparin is a low molecular weight heparin (LMWH) which, when bound to antithrombin III (ATIII), accelerates the inactivation of factor II and factor Xa.
Mixtures: FRAXIPARINE 0.3 MLProducts: FRAXODI 19.000I.E.AN-XA/ML, /ml InjektionslösungOxcarbazepine
go.drugbank.com/drugs/DB00776ApprovedInvestigationalOxcarbazepine is an anti-epileptic medication used in the treatment of partial onset seizures that was first approved for use in the United States in 2000. It is a structural derivative of carbamazepine and exerts a majority of its activ...
Categories: P-glycoprotein inducers, P-glycoprotein substratesProducts: Oxtellar XR, KALLION XRMeloxicam
go.drugbank.com/drugs/DB00814ApprovedInvestigationalVet approvedMeloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve various types of pain, including pain caused by musculoskeletal conditions, osteoarthritis, and rheumatoid arthritis. With a longer half-life than most other NSAI...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: NIFLAMIN® PL FORTE 15 MG, NIFLAMIN® PL CAPSULAS 7.5 MGPeracetic acid
go.drugbank.com/drugs/DB14556InvestigationalA liquid that functions as a strong oxidizing agent. It has an acrid odor and is used as a disinfectant.
Products: Pu Us Pure, Pu Us LemonGlycopyrronium
go.drugbank.com/drugs/DB00986ApprovedInvestigationalVet approvedGlycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers. They are both quaternary ammonium compounds and long acting muscarinic antagonists. It is one of the most commonly prescribed anticholinergi...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: Glyrx-PF, GLYCO-POlopatadine
go.drugbank.com/drugs/DB00768ApprovedOlopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine work...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: OLODINA PF®, OLOFTAL PF®Clonidine
go.drugbank.com/drugs/DB00575ApprovedInvestigationalClonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors. This activity is useful for the treatment of hypertension, severe pain, and ADHD. Clonidine was granted FDA approval on 3 September 1974.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Nexiclon XR, Onyda XRPaclitaxel
go.drugbank.com/drugs/DB01229ApprovedInvestigationalVet approvedPaclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree whi...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: PAXUS PM (30 MG), PAXUS PM (100 MG)Ketoprofen
go.drugbank.com/drugs/DB01009ApprovedInvestigationalVet approvedKetoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsInternational brands: Toprec