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Iohexol
go.drugbank.com/drugs/DB01362ApprovedInvestigationalIohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. … Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Categories: Compounds used in a research, industrial, or household settingSynonyms: N,N'-Bis(2,3-dihydroxypropyl)-5-(N-(2,3-dihydroxypropyl)acetamido)-2,4,6-triiodoisophthalamideDronabinol
go.drugbank.com/drugs/DB00470ApprovedIllicitInvestigationalDue to its evidence as an appetite stimulant and an anti-nauseant, Dronabinol is approved for use in anorexia associated with weight loss in patients with AIDS and for the treatment of nausea and vomiting … CB2 receptors are mainly located in the peripheral nervous system and can be found on lymphoid tissue where they are involved in regulation of immune function [A32676].
Categories: Cannabinoids and similars, Alimentary Tract and MetabolismProducts: Marinol Cap 10mgHuman thrombin
go.drugbank.com/drugs/DB11571ApprovedInvestigationalThis transformation mimics the final coagulation cascade step which involves the clotting mass that adheres to the wound surface and achieves hemostasis and sealing of open tissues. … Furthermore, human thrombin is manufactured by chromatographic purification of prothrombin from cryo-poor plasma followed by activation with calcium chloride [FDA Label].
Mixtures: EVICEL Fibrin Sealant (Human) Solution, 50-90 mg/ml, 800-1200 IU/mlProducts: THROMBIRAAS1000 UIMelanoma antigen preferentially expressed in tumors
go.drugbank.com/bio_entities/BE0010493TargetHumansIn the nucleus, the CRL2(PRAME) complex is recruited to epigenetically and transcriptionally active promoter regions bound by nuclear transcription factor Y (NFY) and probably plays a role in chromstin … and apoptosis (PubMed:16179254)
Polypeptides: Melanoma antigen preferentially expressed in tumorsEquisetum arvense top
go.drugbank.com/drugs/DB14349ApprovedWithdrawnEquisetum arvense top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Products: Silica Aqueous Extract 500mg, BABOR Cleansing Gel and TonicAlirocumab
go.drugbank.com/drugs/DB09302ApprovedInvestigationalAlirocumab is a biopharmaceutical that obtained FDA approval in July 2015 as a second line treatment for high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of … diet and statin treatment.
Categories: Amino Acids, Peptides, and ProteinsProducts: PRALUENT®150MG/ML SOLUCIÓN INYECTABLE, PRALUENT SOLUTION FOR INJECTION IN A PRE-FILLED PEN 75MG/MLDextromethorphan
go.drugbank.com/drugs/DB00514ApprovedInvestigationalDextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. … [A215412] Although similar in structure to other opioids, it has minimal interaction with opioid receptors.[A215412] Dextromethorphan was granted FDA approval before 3 December 1957.
Mixtures: Acetaminophen 500mg, Dextromethorphan HBr 10mg, Guaifenesin 200mg, Phenylephrine HCl 5mg, BENICAL 10 MG+20MG+2MG/5 ML SURUP, 100 MLCategories: Cough and Cold Preparations, Opium Alkaloids and DerivativesLipoic acid
go.drugbank.com/drugs/DB00166ApprovedInvestigationalNutraceuticalA vitamin-like antioxidant.
Mixtures: Folic-KCategories: Compounds used in a research, industrial, or household setting, Enzymes and CoenzymesAurothioglucose
go.drugbank.com/drugs/DB09121ApprovedWithdrawnContemporary research on the effect of gold salts treatment began in 1935, primarily to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis [A32326]. … and others, which are far more effective.
Categories: Antiinflammatory and Antirheumatic ProductsProducts: Solganal Inj 50mg/mlAntilymphocyte immunoglobulin (horse)
go.drugbank.com/drugs/DB09312ApprovedInvestigationalIt is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen. … Induction of T cell apoptosis and resulting T-cell lymphopenia found in vivo is credited for its therapeutic effect in these conditions.
Categories: Fluids and Secretions, Amino Acids, Peptides, and ProteinsProducts: Atgam Sterile Solution IV 50mg/ml, ATGAM 50MG/ML STERILE SOLUTION (5ML AMP)