Search

Displaying results 991 - 1000 of 5897 in total
  1. Drug

    Pravastatin

    go.drugbank.com/drugs/DB00175
    ApprovedInvestigational

    [T274] This drug was developed by Sankyo Co. Ltd.; however, the first approved pravastatin product was developed by Bristol Myers Squibb and FDA approved in 1991. … The manufacturing process is followed by the hydrolysis of the lactone group and the biological hydroxylation with _Streptomyces carbophilus_ to introduce the allylic 6-alcohol group.[T239]

    Products: PRAVASTATINA MYLAN GENERICS, PRAVASTATINA DOC GENERICI
  2. Drug

    Hexafluronium

    go.drugbank.com/drugs/DB00941
    Approved

    It is known to bind and block the activity of plasma cholinesterases. … Hexafluronium bromide is a neuromuscular blocking agent used in anesthesiology to prolong and potentiate the skeletal muscle relaxing action of suxamethonium during surgery.

  3. Drug

    Trastuzumab deruxtecan

    go.drugbank.com/drugs/DB14962
    ApprovedInvestigational

    The cleavable peptide linker used to bind the antibody and drug in this product distinguishes it from other members of its class. … Trastuzumab deruxtecan is a HER2-directed antibody attached to a topoisomerase inhibitor that is approved for use in certain types of treatment-resistant HER2-positive cancers.

  4. Drug

    2'-Deoxycytidine-5'-Monophosphate

    go.drugbank.com/drugs/DB03798
    Experimental

    A deoxycytosine nucleotide containing one phosphate group esterified to the deoxyribose moiety in the 2'-,3'- or 5- positions. [PubChem]

  5. Drug

    Mevastatin

    go.drugbank.com/drugs/DB06693
    Experimental

    It has served as one of the lead compounds for the development of the synthetic compounds used today. … The compound was proposed to bind to the reductase enzyme and was named compactin.

  6. Drug

    Potassium alum

    go.drugbank.com/drugs/DB09087
    ApprovedWithdrawn

    Potassium alum is considered by the FDA as a generally recognized as safe (GRAS) substance. It is an inorganic salt, also called potassium aluminum sulfate with a formula of AlK(SO4)2 that is predominantly produced in the dodecahydrate f...

    Mixtures: Gingicord W Epineph and Alum Size No 1, Gingicord W Epineph and Alum Size No 3Products: Gingibraid W Alum Pot Sulf 0a 0.25mg/2.5cm, Gingibraid W Alum Pot Sulf 1a 0.35mg/2.5cm
  7. Drug

    Phenacemide

    go.drugbank.com/drugs/DB01121
    Approved

    Phenacemide is used to control certain seizures in the treatment of epilepsy. This medicine acts on the central nervous system (CNS) to reduce the number and severity of seizures.

  8. Drug

    Axicabtagene ciloleucel

    go.drugbank.com/drugs/DB13915
    ApprovedInvestigational

    [L40054] The development of resulted from early preclinical studies conducted by a group of researchers at the National Cancer Institute (NCI), who demonstrated that T cells expressing an anti-CD19 CAR … It is marketed under the brand name Yescarta and is used to treat large B-cell lymphomas and follicular lymphoma in adults.

  9. Drug

    Progesterone

    go.drugbank.com/drugs/DB00396
    ApprovedInvestigationalVet approved

    Progesterone is used in various contraceptive preparations to prevent ovulation and fertilization [T481], [A175612] as well as in other formulations to promote and support pregnancy. … A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss [A175609].

  10. Drug

    Alglucerase

    go.drugbank.com/drugs/DB00088
    ApprovedWithdrawn

    The modification alters the sugar residues at the non-reducing ends of the oligosaccharide chains of the glycoprotein so that they are predominantly terminated with mannose residues.