Phenacemide

DB01121ApprovedSmall molecule

Phenacemide is used to control certain seizures in the treatment of epilepsy. This medicine acts on the central nervous system (CNS) to reduce the number and severity of seizures.

Mechanism: Phenacemide binds to and blocks neuronal sodium channels or voltage sensitive calcium channels. This blocks or suppresses neuronal depolarization and hypersynchronization. Hypersynchronization is what often causes seizures.
Curator reviewed
Primary indication: Used to control certain seizures in the treatment of epilepsy.Curator reviewed
Formula / weight: C₉H₁₀N₂O₂ · 178.1879 g/mol (avg)

Resolves to

Compound

UNIIPAI7J52V09CAS63-98-9ChEMBLCHEMBL918ChEBI8049PubChem4753KEGGD00504

Clinical / RWD

RxNorm33253ATCN03AX07PharmGKBPA164745309

Structure

InChIKeyXPFRXWCVYUEORT-UHFFFAOYSA-NSMILESNC(=O)NC(=O)CC1=CC=CC=C1

Targets

P35498SCN1A

What you can answer from here — as of September 23, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

809Drug interactionsStructured to mechanism, not free text

1ATC codeIncluding every combination product, plus 6 drug categories

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Phenacemide, and which of those have an active Phase 3 trial?

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