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Displaying results 991 - 1000 of 10000 in total
  1. Target

    Serine/threonine-protein kinase Nek1

    go.drugbank.com/bio_entities/BE0009496
    TargetHumans

    Involved in cilium assembly (PubMed:21211617) … In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death (PubMed:20230784). May be implicated in the control of meiosis (By similarity).

    Synonyms: Never in mitosis A-related kinase 1
  2. Drug

    Eftrenonacog alfa

    go.drugbank.com/drugs/DB11608
    Approved

    It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H … Hemophilia B is a blood disorder with an incidence of approximately once every 30,000 male births in all populations and ethnic groups [A31557].

    Synonyms: Recombinant human coagulation factor IX, FC Fusion protein, Coagulation factor IX recombinant immunoglubulin g1 fusion protein
  3. Drug

    Sumatriptan

    go.drugbank.com/drugs/DB00669
    ApprovedInvestigational

    [L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. … Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.

    Synonyms: (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide, 3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamideProducts: Imitrex Inj 12mg/ml, SUMATRIPTAN-HEXAL N 50MG
  4. Target

    Nuclear factor NF-kappa-B

    go.drugbank.com/bio_entities/BE0004903
    TargetHumans

    NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. … NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family.

    Synonyms: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
  5. Drug

    Glucosamine

    go.drugbank.com/drugs/DB01296
    Approved

    [A231894,A232289] It is currently not approved as a prescription product by the FDA, but is widely available over the counter. … Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation.

    Mixtures: flexijoint 3-in-1 Joint Care Powder, OSTEOACTIV 3-in-1 Joint Formula PowderProducts: Procosa II Tablet, Nn Bio-Glucosamine 500 Tablet
  6. Drug

    Alanine

    go.drugbank.com/drugs/DB00160
    ApprovedInvestigationalNutraceutical

    Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. … It is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and the central nervous system.

    Mixtures: Aminosyn II in Dextrose, Aminosyn II in Dextrose
  7. Drug

    Avobenzone

    go.drugbank.com/drugs/DB09495
    ApprovedInvestigational

    It is included in many commercially available sunscreens which are used as wide spectrum sunscreens. … Avobenzone is very sensitive to light, to increase its stability and duration of action, photostablizers are added in the sunscreen product. Avobenzone has an absorption maximum of 357 nm.

    Mixtures: American Crew All-IN-one Face Balm, American Crew All-IN-one Face Balm SPF 15Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Estradiol

    go.drugbank.com/drugs/DB00783
    ApprovedInvestigationalVet approved

    Estradiol is a naturally occurring hormone circulating endogenously in females. … It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes.

    Mixtures: KLIOGEST N, KLIOGEST NProducts: AKROFOLLINE 5 MG/ML IM AMPUL
  9. Drug

    Somatrem

    go.drugbank.com/drugs/DB09098
    ApprovedWithdrawn

    Despite the ability of almost all contemporary recombinant growth hormones to cause definite and demonstrable increases in growth rate in patients who are administered the drug, the use of these agents … continues to be mired in persistent bioethical debate [A32292].

    Mixtures: Protropin Inj Pws 10mg/vial, Protropin - Kit Im Sc 10mg/vial
  10. Drug

    Sildenafil

    go.drugbank.com/drugs/DB00203
    ApprovedInvestigational

    in some countries [L5656]. … the public in 1998 [A175732], continues to see millions of prescriptions written for it internationally.

    Categories: Drugs Used in Erectile DysfunctionProducts: EROS INN 50 MG TABLETAS, SILDENAFIL IG FARMACEUTICI