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Displaying results 9991 - 10000 of 10000 in total
  1. Drug

    Pimicotinib

    go.drugbank.com/drugs/DB18972
    Investigational

    Pimicotinib is under investigation in clinical trial NCT05804045 (Study of Pimicotinib (ABSK021) for Tenosynovial Giant Cell Tumor (MANEUVER)). It was initially developed by Abbisko Therapeutics Co in collaboration with Merck KGaA. Pimic...

    Synonyms: 1-Pyrrolidinecarboxamide, 3,3-dimethyl-N-[6-methyl-5-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-2-oxo-, 3,3-Dimethyl-N-[6-methyl-5-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-2-oxo-1-pyrrolidinecarboxamideCategories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Baxdrostat

    go.drugbank.com/drugs/DB19090
    ApprovedInvestigational

    It targets aldosterone excess, a primary underlying driver of treatment resistance and organ damage in cardiovascular diseases [A275512, A275515]. … On May 18, 2026, baxdrostat was approved by the FDA as a first-in-class aldosterone synthase inhibitor for the treatment of hypertension in combination with other antihypertensive drugs [L56189].

    Synonyms: (+)-(r)-n-(4-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydroisoquinolin-8-yl)propionamide, N-((8r)-5,6,7,8-tetrahydro-4-(1,2,3,4-tetrahydro-1-methyl-2-oxo-6-quinolinyl)-8-isoquinolinyl)propanamideCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  3. Drug

    Isuzinaxib

    go.drugbank.com/drugs/DB19109
    Investigational

    Isuzinaxib is under investigation in clinical trial NCT05758896 (Study of APX-115 in Contrast Induced Acute Kidney Injury in Subjects Undergoing PCI).

    Synonyms: 1-(pyridin-2-yl)-3-phenyl-4-propyl-1h-pyrazol-5-ol, 1h-pyrazol-5-ol, 3-phenyl-4-propyl-1-(2-pyridinyl)-Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Farglitazar

    go.drugbank.com/drugs/DB19311
    Investigational

    Synonyms: L-TYROSINE, N-(2-BENZOYLPHENYL)-O-(2-(5-METHYL-2-PHENYL-4-OXAZOLYL)ETHYL)-, N-(O-BENZOYLPHENYL)-O-(2-(5-METHYL-2-PHENYL-4-OXAZOLYL)ETHYL)-L-TYROSINECategories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Mitomycin A

    go.drugbank.com/drugs/DB19369
    Experimental

    Synonyms: Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-6,8a-dimethoxy-5-methyl-, (1as,8s,8ar,8bs)-, 6-methoxy analog of mitomycin cCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  6. Drug

    NITHIAMIDE

    go.drugbank.com/drugs/DB19371
    ApprovedWithdrawn

    Synonyms: Acetamide, n-(5-nitro-2-thiazolyl)-, N-(5-nitro-2-thiazolyl)acetamideCategories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Zoxazolamine

    go.drugbank.com/drugs/DB19372
    ApprovedWithdrawn

    Synonyms: 2-amino-5-chlorobenzoxazole, 5-chloro-2-benzoxazolamineCategories: Heterocyclic Compounds, 2-Ring
  8. Drug

    Syrosingopine

    go.drugbank.com/drugs/DB19379
    ApprovedWithdrawn

    Synonyms: -dimethoxy-3.beta.,20.alpha.-yohimban-16.beta.-carboxylate 4-hydroxy, Yohimban-16-carboxylic acid, 18-((4-((ethoxycarbonyl)oxy)-3,5-dimethoxybenzoyl)oxy)-11,17-dimethoxy-, methyl ester, (3.beta.,16.beta.,17.alpha.,18.beta.,20.alpha.)-Categories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Calcimycin

    go.drugbank.com/drugs/DB19408
    Investigational

    Primarily used as a biochemical tool for studying divalent cations in biological systems, Calcimycin also exhibits antibiotic activity against gram-positive bacteria and fungi.

    Synonyms: Antibiotic a-23187, 4-benzoxazolecarboxylic acid, 5-(methylamino)-2-(((2r,3r,6s,8s,9r,11r)-3,9,11-trimethyl-8-((1s)-1-methyl-2-oxo-2-(1h-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)-Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-Ring
  10. Drug

    Azadirachtin

    go.drugbank.com/drugs/DB19419
    Investigational

    Azadirachtin is under investigation in clinical trial NCT06617026 (Short-term Outcome of Medical vs. Surgical Management of Chronic Anal Fissure).

    Synonyms: Azadirachtin aCategories: Compounds used in a research, industrial, or household setting