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DPM-1001
go.drugbank.com/drugs/DB18390ExperimentalSynonyms: methyl (R)-4-((3S,5R,7R,8R,9S,10S,13R,14S,17R)-7-hydroxy-10,13-dimethyl-3-((4-((pyridin-2-ylmethyl)amino)butyl)amino)hexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate, Methyl (3β,5α,7α)-7-hydroxy-3-[[4-[(2-pyridinylmethyl)amino]butyl]amino]cholan-24-oateSalts: DPM-1001 maleateEfavirenz
go.drugbank.com/drugs/DB00625ApprovedInvestigationala high risk for HIV transmission. … Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human
Synonyms: (S)-6-chloro-4-(Cyclopropylethynyl)-1,4-dihydro-(S)-6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one, 6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-oneMixtures: Efatriten 600 mg/200 mg/245 mg Filmtabletten, Padviram 600 mg/200 mg/245 mg - FilmtablettenMagnesium hydroxide
go.drugbank.com/drugs/DB09104ApprovedInvestigationalIt can also be used topically as a deodorant or for the relief of canker sores (aphthous ulcers). … Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form.
Mixtures: TRIGAST 10 MG/800 MG/165 MG ÇİĞNEME TABLETİ, 6 ADET, ACİDPASS 10 MG/800 MG/165 MG ÇİĞNEME TABLETİ, 2 ADETProducts: MAGNESIE CALCINEE SABA 400 MG SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 100 G, MAGNESIE CALCİNEE 400 MG SÜSPANSİYON HAZIRLAMAK İÇİN KURU TOZ, 100 GAlprostadil
go.drugbank.com/drugs/DB00770ApprovedInvestigationalAlprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. … [A257068,A257088] Alprostadil is also used in neonatal patients with congenital heart defects that depend on a patent ductus for survival until corrective or palliative surgery can be performed.
Categories: Prostaglandins ESynonyms: PGE-1, (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acidDidanosine
go.drugbank.com/drugs/DB00900ApprovedInvestigationalA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. … Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative
Categories: Heterocyclic Compounds, 2-RingSynonyms: 9-((2R,5S)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one, 9-((2S,5R)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-olDexamethasone
go.drugbank.com/drugs/DB01234ApprovedInvestigationalVet approvedDexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic … [L10695] In a press release for the Randomized Evaluation of COVID-19 Therapy (RECOVERY) trial on 16 June 2020, dexamethasone was recommended for use in COVID-19 patients with severe respiratory symptoms
Mixtures: LERGOSIN-A, NETILDEX GOZ DAMLASI %0,1 DEKSAMETAZON + %0,3 NETILMISIN 0,3 ML × 20 ADETCategories: P-glycoprotein inducers, P-glycoprotein inhibitorsPentoxifylline
go.drugbank.com/drugs/DB00806ApprovedInvestigationalA branded product, PENTOXIL, marketed by Upsher-Smith Laboratories, and generic forms marketed by Valeant Pharmaceuticals and APOTEX have been available since the late 1990s.[L30300] … [A226410, A226415, A226455] More recently, PTX has been suggested as a possible treatment for COVID-19-induced pulmonary complications due to its ability to regulate the production of inflammatory cytokines
International brands: Ao Le Ni, An Ruo NingMixtures: Betamethasone Dipropionate 0.05% / Minoxidil 5% / Niacinamide 2% / Pentoxifylline 0.5%Zoledronic acid
go.drugbank.com/drugs/DB00399ApprovedInvestigationalZoledronic acid, or CGP 42'446,[A203120] is a third generation, nitrogen containing bisphosphonate similar to [ibandronic acid], [minodronic acid], and [risedronic acid]. … [A203120] Zoledronic acid was granted FDA approval on 20 August 2001.[L13712]
Salts: Zoledronate D,L-Lysine MonohydrateCategories: Heterocyclic Compounds, 1-RingFish oil
go.drugbank.com/drugs/DB13961ApprovedInvestigationalNutraceuticalHowever, prescription-only fish oil products are sometimes prescribed for individuals who demonstrate severe (>= 500 mg/dL) hypertriglyceridemia [FDA Label]. … Fish oil is a component of SMOFLIPID, which was FDA approved in July 2016.
Synonyms: Omega-3 fish oil, Fish oil containing omega-3 acidsMixtures: OGAMIX(Evening primrose oil 500 mg, Lecithin oil 500 mg, Fish oil 125 mgand Vitamin E 10 mg Soft Gelatin Capsule), SMOFlipid 200 mg/ml Emulsion zur InfusionVoriconazole
go.drugbank.com/drugs/DB00582ApprovedInvestigationalVoriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. … [A236050] Voriconazole was approved by the FDA under the trade name Vfend on May 24, 2002.[L34660]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InhibitorsSynonyms: (R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol, (αR,βS)-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol