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Displaying results 1011 - 1020 of 10000 in total
  1. Drug

    Vitamin E

    go.drugbank.com/drugs/DB00163
    ApprovedInvestigationalNutraceuticalVet approved

    In 1922, vitamin E was demonstrated to be an essential nutrient[A32448]. … Vitamin E acts as an antioxidant, protecting cell membranes from oxidative damage[A176104].

    International brands: Aquasol E, Amino-Opti-EMixtures: Co-q10 M.R.B. 100mg and Vitamin E, E 400iu W Selenium 100mcg
  2. Drug

    Dasatinib

    go.drugbank.com/drugs/DB01254
    ApprovedInvestigational

    [A2226] The use of dasatinib was first approved by the FDA in 2006.[L45171,L45186] … [A2226,A11377] Also, mutations in the kinase domain of BCR-ABL may lead to relapse during imatinib treatment.

    Synonyms: N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamideProducts: DASATINIB EG
  3. Drug

    Calcitriol

    go.drugbank.com/drugs/DB00136
    ApprovedInvestigationalNutraceutical

    to [DB00146] in the liver and kidneys. … It is also available in topical form for the treatment of mild to moderate plaque psoriasis in adults.

    Products: CALCITRIOLO EG
  4. Drug

    Cimetidine

    go.drugbank.com/drugs/DB00501
    ApprovedInvestigational

    It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.

    Synonyms: N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine, N-cyano-N'-methyl-N''-(2-([(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl)ethyl)guanidineProducts: Gen-cimetidine Tablets 200mg, Cimetidine in Sodium Chloride
  5. Drug

    Leuprolide

    go.drugbank.com/drugs/DB00007
    ApprovedInvestigational

    Prolonged activation of GnRHR results in significant downregulation of sex steroid levels, which is primarily responsible for the clinical efficacy of leuprolide in diverse conditions, including advanced … [L13781, L13790] Leuprolide remains frontline therapy in all conditions for which it is indicated for use.

    Products: ELIGARD 22.5 MG ENJ. COZ. ICIN S.C. TOZ ICEREN SIRINGA VE COZUCU ICEREN SIRINGA, 1 ADET
  6. Drug

    Methylprednisolone

    go.drugbank.com/drugs/DB00959
    ApprovedInvestigationalVet approved

    [A188811] It was first described in the literature in the late 1950s.[A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. … [L10785] In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with long-term immunosuppression.

    Mixtures: Physicians EZ Use M-pred, Physicians EZ Use M-predCategories: Compounds used in a research, industrial, or household setting
  7. Drug

    Cobicistat

    go.drugbank.com/drugs/DB09065
    ApprovedInvestigational

    More specifically, cobicistat is indicated to increase systemic exposure of atazanavir or darunavir (once daily dosing regimen) in combination with other antiretroviral agents in the treatment of HIV-1

    Mixtures: GENVOYA 150MG/150MG/200MG/10MG FILM KAPLI TABLET, 90 ADET, GENVOYA 150MG/150MG/200MG/10MG FILM KAPLI TABLET, 30 ADETCategories: Antivirals used in combination for the treatment of HIV infections
  8. Drug

    Sugemalimab

    go.drugbank.com/drugs/DB16641
    ApprovedInvestigational

    [L53333] In combination with platinum-based chemotherapy, sugemalimab is a first-line treatment indicated for adult populations with metastatic non-small cell lung cancer (NSCLC) with no sensitising EGFR … [L32868] Sugemalimab was under investigation in the clinical trial NCT03802591 (A Study of CS1001 in Subjects With Gastric Adenocarcinoma or Gastro-esophageal Junction Adenocarcinoma).

  9. Drug

    Mirtazapine

    go.drugbank.com/drugs/DB00370
    ApprovedInvestigational

    [A178144,L6160] In addition to its beneficial effects in depression, mirtazapine has been reported to be efficacious in the off-label management of various other conditions. … Mirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994.

    Products: MIRTAZAPINA EG, MIRTAZAPINA EG STADA
  10. Drug

    Levodopa

    go.drugbank.com/drugs/DB01235
    ApprovedInvestigational

    The first developed drug product that was approved by the FDA was a levodopa and carbidopa combined product called Sinemet that was approved on May 2, 1975[A177781,L6133]. … Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent metabolism until after

    Mixtures: LEV/CAR/EN AL100/25/200, LEV/CAR/EN AL200/50/200