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3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONE
go.drugbank.com/drugs/DB07385ExperimentalSynonyms: 3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONEPindolol
go.drugbank.com/drugs/DB00960ApprovedInvestigational[A231064] Pindolol was granted FDA approval on 3 September 1982.[L32348] … Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension.
Categories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT1A Receptor AntagonistsSynonyms: 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)-propan-2-ol, 1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-olLofexidine
go.drugbank.com/drugs/DB04948ApprovedInvestigationalLofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved for the treatment of opioid withdrawal in the United Kingdom in 1992. … [T210] Lofexidine was then repurposed for the treatment of opioid withdrawal, as it was seen to be more economical and have fewer side effects than clonidine.
Categories: Serotonin 5-HT2 Receptor Agonists, Adrenergic alpha-2 Receptor AgonistsSynonyms: 2-(alpha-(2,6-Dichlorophenoxy)ethyl)2-imidazolinePlumbagin
go.drugbank.com/drugs/DB17048InvestigationalPlumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.[A253102]
Categories: Compounds used in a research, industrial, or household settingSynonyms: 5-hydroxy-2-methyl-1,4-naphthalenedione(3Z,6S)-6-Chloro-1-(2-{[(5-chloro-1-benzothiophen-3-yl)methyl]amino}ethyl)-3-({2-[(2R)-2-piperidinyl]ethyl}imino)-2-piperazinol
go.drugbank.com/drugs/DB07521ExperimentalSynonyms: (3S)-3-Chloro-4-[2-[(5-chloro-1-benzothiophen-3-yl)methylamino]ethyl]-6-[2-[(2R)-piperidin-2-yl]ethylamino]-3,5-dihydro-2H-pyrazin-5-ol, (3Z,6S)-6-Chloro-1-(2-{[(5-chloro-1-benzothiophen-3-yl)methyl]amino}ethyl)-3-({2-[(2R)-2-piperidinyl]ethyl}imino)-2-piperazinolBethanechol
go.drugbank.com/drugs/DB01019ApprovedBethanechol is a synthetic ester that was initially synthesized in 1935. … [A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous
Synonyms: 2-(carbamoyloxy)-N,N,N-trimethylpropan-1-aminium, 2-carbamoyloxypropyl-trimethylazaniumProducts: Myocholine - Glenwood Tabletten 25 mg, ยูโคลีน (5 มิลลิกรัม)Neoarsphenamine
go.drugbank.com/drugs/DB18729ApprovedWithdrawnSynonyms: Sulfoxylic acid, mono(((5-((3-amino-4-hydroxyphenyl)diarsenyl)-2-hydroxyphenyl)amino)methyl) ester, sodium salt (1:1), Sodium p,p'-dihydroxy-m,m'-diaminoarsenobenzene-n-monomethanol sulfoxylateAngiotensin II
go.drugbank.com/drugs/DB11842ApprovedInvestigationalAs of December 21, 2017 the FDA approved La Jolla Pharmaceutical's Giapreza (angiotensin II) Injection for Intravenouse Infusion for the indication of acting as a vasoconstrictor to increase blood pressure … Shock is the inability to maintain blood flow to vital tissues and the potential resultant organ failure and death within hours, no matter young or o ld.
Synonyms: 5-L-isoleucineangiotensin II, 5-isoleucine-angiotensin IISerotonin
go.drugbank.com/drugs/DB08839InvestigationalNutraceuticalFor temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and lethargy. Not evaluated by the FDA, homeopathic product.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 3-(2-Aminoethyl)-1H-indol-5-ol, 5-HTUlevostinag
go.drugbank.com/drugs/DB14721InvestigationalUpon intratumoral (IT) administration, STING agonist MK-1454 binds to STING and activates the STING pathway, which promotes IKK-related kinase TANK-binding kinase 1 (TBK1) signaling and activates nuclear … factor-kappa B (NF-kB) and interferon regulatory factor 3 (IRF3) in immune cells in the tumor microenvironment; this leads to the production of pro-inflammatory cytokines, including interferons (IFNs)
Synonyms: Guanosine, (p(r))-2'-deoxy-2'-fluoro-5'-o-((r)-hydroxymercaptophosphinyl)-p-thio-.beta.-d-arabino-adenylyl-(3'->5')-3'-deoxy-3'-fluoro-, cyclic nucleotide, Cyclo((p3'r,2's)-2'-deoxy-2'-fluoro-p-thioadenylyl-(3'->5')-(p2'r)- 3'-deoxy-3'-fluoro-p-thioguanylyl-(2'->5'))