Search
Tumor necrosis factor receptor superfamily member 18
go.drugbank.com/bio_entities/BE0010519TargetHumansMediated NF-kappa-B activation via the TRAF2/NIK pathway … Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death.
Polypeptides: Tumor necrosis factor receptor superfamily member 18Synonyms: Activation-inducible TNFR family receptorLow-density lipoprotein receptor-related protein 6
go.drugbank.com/bio_entities/BE0012061TargetHumansComponent of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes (PubMed:11357136, PubMed:11448771
Polypeptides: Low-density lipoprotein receptor-related protein 6Tyrosine-protein phosphatase non-receptor type 2
go.drugbank.com/bio_entities/BE0012706TargetHumansNegatively regulates tumor necrosis factor-mediated signaling downstream via MAPK through SRC dephosphorylation. … Non-receptor type tyrosine-specific phosphatase that dephosphorylates receptor protein tyrosine kinases including INSR, EGFR, CSF1R, PDGFR.
Polypeptides: Tyrosine-protein phosphatase non-receptor type 2Tumor necrosis factor receptor superfamily member EDAR
go.drugbank.com/bio_entities/BE0021253TargetHumansReceptor for EDA isoform A1, but not for EDA isoform A2. Mediates the activation of NF-kappa-B and JNK. May promote caspase-independent cell death
Polypeptides: Tumor necrosis factor receptor superfamily member EDARSynonyms: EDA-A1 receptor, Ectodysplasin-A receptorT cell receptor beta variable 6-5
go.drugbank.com/bio_entities/BE0021562TargetHumansV region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).
Polypeptides: T cell receptor beta variable 6-5Luspatercept
go.drugbank.com/drugs/DB12281ApprovedInvestigational[L42455] Luspatercept is novel in that it ameliorates anemia via action on late-stage erythropoiesis, in contrast to typical erythropoiesis-stimulating agents (ESAs), such as [darbepoetin alfa] and [epoetin … Luspatercept is a recombinant fusion protein comprised of a modified extracellular domain of activin receptor type IIB fused to the FC domain of human IgG1.
Olodaterol
go.drugbank.com/drugs/DB09080ApprovedInvestigationalBeta2-adrenergic receptors are membrane-bound receptors that are normally activated by endogenous epinephrine whose signalling, via a downstream L-type calcium channel interaction, mediates smooth muscle … Activation of the receptor stimulates an associated G protein which then activates adenylate cyclase, catalyzing the formation of cyclic adenosine monophosphate (cAMP) and protein kinase A (PKA).
Categories: Adrenergic beta-1 Receptor Agonists, Adrenergic beta-2 Receptor AgonistsAlginic acid
go.drugbank.com/drugs/DB13518ApprovedInvestigationalWithdrawnAlginic acid is a linear polymer consisted of L-glucuronic acid and D-mannuronic acid residues connected via 1,4-glycosidic linkages [A32961]. … Alginic acid, also referred to as algin or alginate, is a hydrophilic or anionic polysaccharide isolated from certain brown seaweed (_Phacophycae_) via alkaline extraction.
Polysorbate 20
go.drugbank.com/drugs/DB11178ApprovedIt is composed of 20 repeated units of polyethylene glycol via ethoxylation.
alpha-Tocopherol acetate
go.drugbank.com/drugs/DB14003ApprovedAlpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) s...
Mixtures: Viva CT Prenatal, Vita-Rx Diabetic Vitamin