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Palbociclib
go.drugbank.com/drugs/DB09073ApprovedInvestigational[A176810] Palbociclib was developed by Pfizer Inc after the discovery that identified the cyclin-dependent kinases as key regulators of cell growth. … [L5867] It was originally FDA approved on March 2015 for the treatment of HR-positive, HER2-negative advanced or metastatic breast cancer and its indications were updated in April 2019 to include male
Synonyms: 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-8h-pyrido(2,3-d)pyrimidin-7-one, 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7(8H)-oneProducts: REAMPLA 100 MG KAPSÜL, 21 KAPSÜL, REAMPLA 100 MG FİLM KAPLI TABLET, 21 ADETMethyldopa
go.drugbank.com/drugs/DB00968ApprovedInvestigationalMethyldopa works by binding to alpha(α)-2 adrenergic receptors as an agonist, leading to the inhibition of adrenergic neuronal outflow and reduction of vasoconstrictor adrenergic signals. … [A232224] First introduced in 1960 as an antihypertensive agent, methyldopa was considered to be useful in certain patient populations, such as pregnant women and patients with renal insufficiency.
Mixtures: Supres 150 Tab, Supres 250 TabCategories: Adrenergic alpha-2 Receptor Agonists, Central alpha-2 Adrenergic AgonistOlaparib
go.drugbank.com/drugs/DB09074ApprovedInvestigational[L41100, L40908, L43792] It was first approved by the FDA and EU in December 2014,[A246020] and by Health Canada in April 2016.[L42820]
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsSynonyms: 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-oneTigecycline
go.drugbank.com/drugs/DB00560ApprovedInvestigationalFood and Drug Administration (FDA) on June 17, 2005. … It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus. It was granted fast-track approval by the U.S.
Synonyms: (4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamideProducts: TİGENEX 50 MG İNFÜZYONLUK ÇÖZELTİ İÇİN TOZ, 10 FLAKON, TYGEPOL 50 MG I.V. İNFÜZYONLUK ÇÖZELTİ İÇİN LİYOFİLİZE TOZ, 10 ADETFlunarizine
go.drugbank.com/drugs/DB04841ApprovedInvestigationalIt is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazineAcebutolol
go.drugbank.com/drugs/DB01193ApprovedInvestigationalThe drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Categories: Adrenergic beta-1 Receptor AntagonistsSynonyms: N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]butanamide, 5'-butyramido-2'-(2-hydroxy-3-isopropylaminopropoxy)acetophenoneMoclobemide
go.drugbank.com/drugs/DB01171ApprovedInvestigationalDue to negligible anticholinergic and antihistaminic actions, moclobemide has been better tolerated than tri- or heterocyclic antidepressants [A31901]. … Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (
Synonyms: 4-Chlor-N-(2-morpholinoethyl)benzamid, p-Chloro-N-(2-morpholinoethyl)benzamideProducts: AURORIX 150 MG FILM KAPLI TABLET, 30 ADET, AURORIX 300 MG FILM KAPLI TABLET, 30 ADETLenograstim
go.drugbank.com/drugs/DB13144ApprovedWithdrawnLenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent.
Synonyms: G-CSF (CHO cell derived), Glycosylated recombinant G-CSFProducts: กราโนไซด์ ชนิดฉีด 250 MCG, กราโนไซด์ ชนิดฉีด 100 MCGLevomenthol
go.drugbank.com/drugs/DB00825ApprovedInvestigational. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration.
Mixtures: KAMFOLIN 150 MG/G+100 MG/G MERHEM, 50 G, SADRÜD % 10 + % 15 JEL, 50 GSynonyms: (1R-(1-α,2-β,5-α))-5-methyl-2-(1-methylethyl)cyclohexanol, (1R,2S,5R)-2-ISOPROPYL-5-METHYLCYCLOHEXAN-1-OLBasiliximab
go.drugbank.com/drugs/DB00074ApprovedInvestigationalA recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also … known as CD25 antigen) on the surface of activated T-lymphocytes.
Categories: Interleukin-2 Receptor Antagonist, Interleukin-2 Receptor Blocking AntibodyProducts: SIMULECT FOR INJECTION 20 mg/vial, SIMULECT® LIOFILIZADO PARA INYECCION 20 MG/VIAL