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Streptococcus pneumoniae type 3 capsular polysaccharide antigen
go.drugbank.com/drugs/DB10321ApprovedInvestigationalIt is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia. … Streptococcus pneumoniae type 3 capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 3 of *Streptococcus pneumoniae*.
Mixtures: PREVENAR 13 SUSPENSION FOR INJECTIONGanirelix
go.drugbank.com/drugs/DB06785ApprovedInvestigationalGanirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques. … Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions.
Products: ORGALUTRAN SOLUTION FOR INJECTION 0.25 mg/0.5 ml, ORGALUTRAN 0.25MG/0.5ML (SOLUTION FOR INJECTION)Testosterone undecanoate
go.drugbank.com/drugs/DB13946ApprovedInvestigational[L35970,L8932,L41355] Testosterone is a critical male hormone that is responsible for the normal growth and development of the male sex organs and for the maintenance of secondary sex characteristics … Testosterone undecanoate is the ester prodrug of [testosterone] and has a mid-chain fatty acid at the carbon 17β position.
Products: NEBIDO 1000MG SOLUTION FOR INJECTIONLithium cation
go.drugbank.com/drugs/DB01356ApprovedInvestigationalWithdrawnIt is also sometimes prescribed as a preventive treatment for migraine disease and cluster headaches. … The active principle in these salts is the lithium ion Li+, which having a smaller diameter, can easily displace K+ and Na+ and even Ca+2, in spite of its greater charge, occupying their sites in several
Synonyms: LI, Li(+)Factor XIII (human)
go.drugbank.com/drugs/DB12909ApprovedInvestigationalFor people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential for management and prevention of bleeding episodes … When activated by thrombin at the site of injury, the FXIII pro-enzyme is cleaved resulting in activation of the catalytic A-subunit and dissociation from its carrier B-subunit.
Pyrazinamide
go.drugbank.com/drugs/DB00339ApprovedInvestigationalA pyrazine that is used therapeutically as an antitubercular agent.
Mixtures: PRO TB 4, PRO TB 3 KIDCategories: Antiinfectives for Systemic Use, Drugs for Treatment of TuberculosisInsulin glargine
go.drugbank.com/drugs/DB00047ApprovedInvestigationalIf left untreated, the body starts to break down fat, instead of glucose, for energy which results in a build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening … Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.
Mixtures: Soliqua SoloStar 100units/mL+33mcg/mL solution for injection in a pre-filled pen, SOLIQUA SOLUTION FOR INJECTION IN A PRE-FILLED PEN 100UNITS/ML + 50MCG/MLProducts: BASALOG 100 IU/mL, SOLUTION FOR INJECTION IN A VIAL, LANTUS 100 Units/ml Solution for injection in a vialLopinavir
go.drugbank.com/drugs/DB01601ApprovedInvestigationalRitonavir is a potent inhibitor of the enzymes responsible for lopinavir metabolism, and its co-administration "boosts" lopinavir exposure and improves antiviral activity. … Lopinavir is marketed and administered exclusively in combination with [ritonavir] - this combination, first marketed by Abbott under the brand name Kaletra in 2000, is necessary due to lopinavir's poor
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseMethylene blue
go.drugbank.com/drugs/DB09241ApprovedInvestigationalThe drug is of potential interest for the treatment of patients with Alzheimer's disease. … The intravenous form of methylene blue is approved by the FDA for the treatment of pediatric and adult patients with acquired methemoglobinemia.
Mixtures: Uro-LCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Tests for Gastric SecretionToripalimab
go.drugbank.com/drugs/DB15043ApprovedInvestigationalOne mechanism by which this occurs is through the overexpression of programmed cell death ligand (PD-L1)[A261506] - the binding of PD-L1 (and PD-L2) to its target receptor (PD-1) results in the inhibition … It was first approved in China in December 2018 for the treatment of unresectable or metastatic melanoma in previously treated patients.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors