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Displaying results 1041 - 1050 of 10000 in total
  1. Drug

    Plumbagin

    go.drugbank.com/drugs/DB17048
    Investigational

    Plumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.[A253102]

    Categories: Compounds used in a research, industrial, or household settingSynonyms: 5-hydroxy-2-methyl-1,4-naphthalenedione
  2. Drug

    Pentavalent Antimony

    go.drugbank.com/drugs/DB13047
    Investigational

    Pentavalent Antimony has been investigated for the treatment of Cutaneous Leishmaniasis.

    Synonyms: Antimony cation (5+)
  3. Drug

    Tubimod

    go.drugbank.com/drugs/DB17745
    Investigational

    Synonyms: V-5 Immunitor, Immunitor V5
  4. Drug

    Tyrosyladenylate

    go.drugbank.com/drugs/DB03325
    Experimental

    Synonyms: 5'-O-(L-Tyrosylsulfamoyl)adenosine
  5. Drug

    Nesolicaftor

    go.drugbank.com/drugs/DB15239
    Investigational

    Nesolicaftor (PTI-428) is under investigation in clinical trial NCT03258424 (Study Assessing PTI-428 Safety, Tolerability, and Pharmacokinetics in Subjects With Cystic Fibrosis on KALYDECO® as Background

    Synonyms: N-(trans-3-(5-((R)-1-hydroxyethyl)-1,3,4-oxadiazol-2-yl)cyclobutyl)-3-phenylisoxazole-5-carboxamide
  6. Drug

    Deupirfenidone

    go.drugbank.com/drugs/DB19056
    Investigational

    Deupirfenidone is under investigation in clinical trial NCT05321420 (LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)).

    Synonyms: 2(1h)-pyridinone, 5-(methyl-d3)-1-phenyl-, 1-phenyl-5-(trideuteriomethyl)-1,2-dihydropyridin-2-oneCategories: Heterocyclic Compounds, 1-Ring
  7. Drug

    (S)-famoxadone

    go.drugbank.com/drugs/DB07778
    Experimental

    Synonyms: (S)-5-Methyl-5-(4-phenoxy-phenyl)-3-phenylamino-oxazolidine-2,4-dione, (S)-famoxadone
  8. Drug

    Levothyroxine

    go.drugbank.com/drugs/DB00451
    ApprovedInvestigational

    deiodination (by type I or type II 5′-deiodinases)[A179941] into its active metabolite T<sub>3</sub>. … [F4636,A35722] In response to Thyroid Stimulating Hormone (TSH) release by the pituitary gland, a normally functioning thyroid gland will produce and secrete T<sub>4</sub>, which is then converted through

    Mixtures: BITIRON 50 MCG/12.5 MCG TABLET, 100 ADET, SYNTHROID® 112 MCG TABLETASCategories: P-glycoprotein inducers, Cytochrome P-450 CYP2C8 Inhibitors
  9. Drug

    R112

    go.drugbank.com/drugs/DB06252
    Experimental

    R112 is an investigational compound developed to treat Allergic Rhinitis. It's mechanism of action is to inhibit SYK kinase.

    Synonyms: 3-((5-FLUORO-2-(3-HYDROXYANILINO)PYRIMIDIN-4-YL)AMINO)PHENOL, 3,3'-((5-FLUORO-2,4-PYRIMIDINEDIYL)DIIMINO)BIS(PHENOL)
  10. Drug

    Dutasteride

    go.drugbank.com/drugs/DB01126
    ApprovedInvestigational

    It is a novel dual 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and irreversible manner. … [A1909] Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary hormonal mediator that plays a role in the development and enlargement of the prostate gland.

    Synonyms: (5α,17β)-N-(2,5-bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide, α,α,α,α',α',α'-hexafluoro-3-oxo-4-aza-5α-androst-1-ene-17β-carboxy-2',5'-xylidideMixtures: Bakumokon 5% Minoxidil, DUODART 0,5 MG/0,4 MG KAPSÜL,7 KAPSÜL