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Granulocyte-macrophage colony-stimulating factor receptor subunit alpha
go.drugbank.com/bio_entities/BE0000628TargetHumansLow affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells
Polypeptides: Granulocyte-macrophage colony-stimulating factor receptor subunit alphaScavenger receptor cysteine-rich type 1 protein M130
go.drugbank.com/bio_entities/BE0003375TargetHumansAcute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage.
Polypeptides: Scavenger receptor cysteine-rich type 1 protein M130Synonyms: Hemoglobin scavenger receptorPutative high affinity immunoglobulin gamma Fc receptor IB
go.drugbank.com/bio_entities/BE0004684TargetHumansMay bind to the Fc region of immunoglobulins gamma with a low affinity compared to FCGR1A. May function in the humoral immune response
Polypeptides: Putative high affinity immunoglobulin gamma Fc receptor IBSynonyms: IgG Fc receptor IB, Fc gamma receptor IB pseudogeneNuclear receptor subfamily 4 group A member 3
go.drugbank.com/bio_entities/BE0008998TargetHumansIn mast cells activated by Fc-epsilon receptor cross-linking, promotes the synthesis and release of cytokines but impairs events leading to degranulation (By similarity).
Polypeptides: Nuclear receptor subfamily 4 group A member 3Synonyms: Nuclear hormone receptor NOR-1, Neuron-derived orphan receptor 1Nuclear receptor subfamily 1 group D member 2
go.drugbank.com/bio_entities/BE0009348TargetHumansActs as a receptor for heme which stimulates its interaction with the NCOR1/HDAC3 corepressor complex, enhancing transcriptional repression. … Binds as a monomer to a response element composed of the consensus half-site motif 5'-[A/G]GGTCA-3' preceded by an A/T-rich 5' sequence (RevRE), or as a homodimer to a direct repeat of the core motif spaced
Polypeptides: Nuclear receptor subfamily 1 group D member 2Synonyms: Rev-erb alpha-related receptor, Orphan nuclear hormone receptor BD73Leukocyte immunoglobulin-like receptor subfamily A member 4
go.drugbank.com/bio_entities/BE0013620TargetHumansFunctions coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G (PubMed:16735691, PubMed:19564354). Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic ...
Polypeptides: Leukocyte immunoglobulin-like receptor subfamily A member 4Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
go.drugbank.com/bio_entities/BE0020703TargetHumansGreatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter (PubMed:10713165, PubMed:20005308, PubMed:21376232).
Polypeptides: Peroxisome proliferator-activated receptor gamma coactivator 1-alphaHistidine
go.drugbank.com/drugs/DB00117ApprovedInvestigationalNutraceuticalAn essential amino acid that is required for the production of histamine.
Mixtures: Aminosyn-PF, Aminosyn-PFPhenylalanine
go.drugbank.com/drugs/DB00120ApprovedInvestigationalNutraceuticalPhenylalanine is an essential aromatic amino acid that is a precursor of melanin, dopamine, noradrenalin (norepinephrine), and thyroxine.
Mixtures: Aminosyn-PF, Aminosyn-PFTryptophan
go.drugbank.com/drugs/DB00150ApprovedInvestigationalNutraceuticalWithdrawnAn essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid)...
Mixtures: Aminosyn-PF, Aminosyn-PF