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Belimumab
go.drugbank.com/drugs/DB08879ApprovedInvestigational[L42630] Belimumab was first approved by the FDA on March 9, 2011,[A251495] making it the newest drug to be approved for the treatment of SLE in more than 50 years. … Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor.
Products: BENLYSTA 200 MG / 1 ML, BENLYSTA SUBCUTÁNEO 200 MG / 1 MLTilmicosin
go.drugbank.com/drugs/DB11471InvestigationalVet approvedTilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with _Mannheimia haemolytica_.
Products: TILMICOSIN 100 mg/ml Oral Solution, EM-MICOFEED 10% GranulesIsosorbide mononitrate
go.drugbank.com/drugs/DB01020ApprovedInvestigationalLike other organic nitrates, isosorbide mononitrate acts as a prodrug for its active metabolite, [nitric oxide], which mediates the therapeutic action of isosorbide mononitrate. … [L11743] Isosorbide mononitrate has a longer duration of action than [nitroglycerin] due to its slow onset of absorption and metabolism.
Synonyms: IS 5-MN, IS-5-MNProducts: Pro-ismn - 60, ISMN AL 100 RETARDPimozide
go.drugbank.com/drugs/DB01100ApprovedA diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome.
Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic IndexProducts: NOROFREN 2 MG TABLET, 10 ADET, NOROFREN 2 MG TABLET, 20 ADETAnastrozole
go.drugbank.com/drugs/DB01217ApprovedInvestigational[A186877,A186955] Anastrozole was first approved for use in the United States in 1995.[L8863] … [L8863] Anastrozole is also related to [exemestane], a steroidal AI, but its non-steroidal nature provides stark advantages including a lack of steroid-associated adverse effects such as weight gain and
Synonyms: α,α,α',α'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrileProducts: Anastrozol 1A Pharma 1 mg - Filmtabletten, Pro-anastrozoleCeftaroline fosamil
go.drugbank.com/drugs/DB06590ApprovedInvestigationalCeftaroline fosamil is a cephalosporin antibacterial indicated for the treatment of the following infections caused by designated susceptible bacteria: Acute bacterial skin and skin structure infections
Synonyms: (6R,7R)-7-[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[4-(1-methylpyridin-1-ium-4-yl)-1,3-thiazol-2-yl]sulfanyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylateCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseKetotifen
go.drugbank.com/drugs/DB00920ApprovedInvestigational[A231204] In the US, it is now used in an over-the-counter ophthalmic formulation for the treatment of itchy eyes associated with allergies,[L32278] and in Canada a prescription-only oral formulation is … It has a similar structure to some other first-generation antihistamines such as [cyproheptadine] and [azatadine].
Categories: Heterocyclic Compounds, 1-Ring, Antihistamines for Systemic UseProducts: FUMAST 1 MG/5 ML SURUP, 100 ML, MITOFEN 1 MG/5 ML SURUP 100 MLOmalizumab
go.drugbank.com/drugs/DB00043ApprovedInvestigationalOmalizumab is a recombinant DNA-derived humanized monoclonal antibody directed against human immunoglobulin E (IgE). … [L50482] It is used to treat a range of immune and inflammatory conditions, including allergies, urticaria, and asthma.[A263507]
Products: XOLAIR ® 150 MG, XOLAIR 150 MG/ML ENJEKSIYONLUK COZELTI İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETIvabradine
go.drugbank.com/drugs/DB09083ApprovedInvestigational≥70 beats per minute, who are not on beta-blockers due to contraindications or already receiving maximum beta-blocker dose. … Recently a new indication was added to treat symptomatic heart failure from dilated cardiomyopathy for patients 6 months or more in age[Label].
Synonyms: 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-oneMixtures: Implicor 50 mg/5 mg Filmtabletten, Implicor 50 mg /7,5 mg FilmtablettenDaptomycin
go.drugbank.com/drugs/DB00080ApprovedInvestigational[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked ring and the N-terminal … Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant _Staphylococcus aureus_ (MSSA/MRSA
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: DAPTOCCORD 500 POWDER FOR SOLUTION FOR INJECTION OR INFUSION 500 MG/VIAL, CUBICIN® 350 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE