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Displaying results 1071 - 1080 of 10000 in total
  1. Drug

    Azithromycin

    go.drugbank.com/drugs/DB00207
    ApprovedInvestigational

    Azithromycin [9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin] is a part of the _azalide_ subclass of macrolides, and contains a 15-membered ring, with a methyl-substituted nitrogen instead of a carbonyl … Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration [A174172]. It was initially approved by the FDA in 1991 [A174175].

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: POLVO PARA RECONSTRUIR A SUSPENSION ORAL, ALENAT ® POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL
  2. Drug

    Quaratusugene ozeplasmid

    go.drugbank.com/drugs/DB19231
    Investigational

    Quaratusugene ozeplasmid is under investigation in clinical trial NCT05062980 (Quaratusugene Ozeplasmid (Reqorsa) in Combination With Pembrolizumab in Previously Treated Non-small Lung Cancer).

    Synonyms: Dna-lipid complex (dotap/cholesterol) plasmid vector (plj143/pkgb2/tusc2, baylor) expressing the tusc2 gene
  3. Drug

    2-(4-hydroxyphenyl)benzo[b]thiophen-6-ol

    go.drugbank.com/drugs/DB08773
    Experimental

    Synonyms: Raloxifene core, 2-(4-hydroxyphenyl)benzo(b)thiophene-6-ol
  4. Drug

    Doxorubicin

    go.drugbank.com/drugs/DB00997
    ApprovedInvestigational

    [A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. … Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic IndexSynonyms: (1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside, (8S-cis)-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
  5. Indication

    Streptococcus Pyogenes Infection

    go.drugbank.com/conditions/DBCOND0038167
    Drugs: Azithromycin · Erythromycin · Omadacycline
    Synonyms: Group A Streptococcal Infections, Group A Streptococcal Infection
  6. Indication

    Hepatitis C Infections

    go.drugbank.com/conditions/DBCOND0072126
    Drugs: Interferon alfa
    Synonyms: Hep non-A non-B, Hepatitis non-A non-B
  7. Drug

    Finasteride

    go.drugbank.com/drugs/DB01216
    ApprovedInvestigational

    It works in a similar fashion as [dutasteride], which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. … Finasteride is a synthetic 4-azasteroid compound [L10565] and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone

    Mixtures: Finasteride 0.1% / Minoxidil 7%, Finasteride 0.1% / Minoxidil 5%Categories: 5-alpha Reductase Inhibitors, Cytochrome P-450 Substrates
  8. Indication

    Born to a mother who is RT-PCR for Zaire ebolavirus

    go.drugbank.com/conditions/DBCOND0135806
    Drugs: Ansuvimab
    Synonyms: Born to a mother who is RT-PCR for Zaire ebolavirus
  9. Indication

    Venous Thrombosis caused by procedures associated with a high incidence of thromboembolic complications

    go.drugbank.com/conditions/DBCOND0106269
    Drugs: Dextran
    Synonyms: Venous Thrombosis caused by procedures associated with a high incidence of thromboembolic complications
  10. Indication

    Anaemic after treatment with a C5 inhibitor for at least three months

    go.drugbank.com/conditions/DBCOND0144822
    Drugs: Pegcetacoplan
    Synonyms: Anaemic after treatment with a C5 inhibitor for at least three months