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Displaying results 1081 - 1090 of 10000 in total
  1. Drug

    Pravastatin

    go.drugbank.com/drugs/DB00175
    ApprovedInvestigational

    Pravastatin is the 6-alpha-hydroxy acid form of [mevastatin].[T303] Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. … [L6142] Pravastatin is made through a fermentation process in which [mevastatin] is first obtained.

    Mixtures: PRAVAFEN® CAPSULASCategories: P-glycoprotein substrates
  2. Drug

    Ganirelix

    go.drugbank.com/drugs/DB06785
    ApprovedInvestigational

    [L43045] The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported in 1998.[A252195] Ganirelix was first approved by the FDA on July 29, 1999. … Ganirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques.

    Products: Ganirelix Astro 0,25 mg/0,5 ml Injektionslösung in einer Fertigspritze, Ganirelix Theramex 0,25 mg/0,5 ml Injektionslösung in einer Fertigspritze
  3. Indication

    Articular Cartilage Defects in the Knee Joint

    go.drugbank.com/conditions/DBCOND0046412
    Drugs: Autologous cultured chondrocytes
    Synonyms: Articular Cartilage Defects in the Knee Joint
  4. Indication

    Squamous Cell Carcinoma In-situ (SCC-is)

    go.drugbank.com/conditions/DBCOND0043487
    Drugs: Aminolevulinic acid
    Synonyms: Squamous cell carcinoma in situ, no ICD-O subtype, Squamous cell carcinoma, no ICD-O subtype
  5. Drug

    Protirelin

    go.drugbank.com/drugs/DB09421
    Approved

    Although not currently available in any FDA-approved product, protirelin is a component of the TRH Test where it is used to test the response of the anterior pituitary gland in conditions such as secondary … It is a tri-peptide tropic hormone, released by the hypothalamus, that stimulates the release of Thyroid Stimulating Hormone (TSH) and prolactin from the anterior pituitary.

    Synonyms: 5-oxo-L-prolyl-L-histidyl-L-prolinamide, L-pyroglutamyl-L-histidyl-L-prolineamideProducts: TRH FERRING 0,2 MG/ML IV ENJEKSIYONLUK COZELTI ICEREN AMPUL, 1 ADET, Relefact Trh Inj 0.2mg/ml
  6. Drug

    Naproxen

    go.drugbank.com/drugs/DB00788
    ApprovedInvestigationalVet approved

    [A179098] Given its overall tolerability and effectiveness, naproxen can be considered a first line treatment for a variety of clinical situations requiring analgesia. … [A179098] Naproxen is available in both immediate and delayed release formulations, in combination with sumatriptan to treat migraines, and in combination with esomeprazole to lower the risk of developing

    Synonyms: (+)-(S)-6-Methoxy-α-methyl-2-naphthaleneacetic acid, (S)-2-(6-Methoxy-2-naphthyl)propanoic acidInternational brands: Bumaflex N, Proxen S
  7. Drug

    Nicotine

    go.drugbank.com/drugs/DB00184
    ApprovedInvestigational

    Nicotine is also important medically because of its presence in tobacco smoke. … Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission.

    Synonyms: (S)-3-(N-methylpyrrolidin-2-yl)pyridine, 3-(2-(N-methylpyrrolidinyl))pyridineCategories: Drugs Used in Addictive Disorders, Drugs Used in Nicotine Dependence
  8. Drug

    Mitoxantrone

    go.drugbank.com/drugs/DB01204
    ApprovedInvestigational

    An anthracenedione-derived antineoplastic agent.

    Categories: Topoisomerase II Inhibitors, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: 1,4-Bis(2-(2-hydroxyethylamino)ethyl)amino)-5,8-dihydroxyanthraquinone
  9. Drug

    Latanoprost

    go.drugbank.com/drugs/DB00654
    ApprovedInvestigational

    Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998. … [A184493] It has been found to be well-tolerated and its use does not normally result in systemic adverse effects like other drugs used to treat elevated intraocular pressure, such as [Timolol].

    Mixtures: Fixapost 50 Mikrogramm/ml + 5 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis, OFTIDON® T SOLUCION OFTALMICACategories: Compounds used in a research, industrial, or household setting, Prostaglandins F, Synthetic
  10. Drug

    Dimethyl fumarate

    go.drugbank.com/drugs/DB08908
    ApprovedInvestigational

    in response to oxidative stress. … [A253942,L43752] The mechanism of action of dimethyl fumarate in multiple sclerosis is not well understood.

    Synonyms: (E)-But-2-enedioic acid dimethyl esterProducts: D-FUMARIC 240 CAPSULAS DE LIBERACIÓN RETARDADA 240 MG, D-FUMARIC 120 CAPSULAS DE LIBERACION RETARDADA 120 MG