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Displaying results 101 - 110 of 152102 in total
  1. Drug

    Tarlatamab

    go.drugbank.com/drugs/DB17256
    ApprovedInvestigational

    [L50748] It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed … across various SCLC disease stages and treatment statuses.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsSynonyms: Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens cd3e (cd3 epsilon, leu-4)), monoclonal antibody single chain (scfv)2-scfc, bispecific
  2. Drug

    Propofol

    go.drugbank.com/drugs/DB00818
    ApprovedInvestigationalVet approved

    Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. … Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries

    Synonyms: 2,6-bis(1-methylethyl)phenolCategories: Hypnotics and Sedatives, Phenols
  3. Drug

    Ursodeoxycholic acid

    go.drugbank.com/drugs/DB01586
    ApprovedInvestigational

    [A256267,A256463] UDCA was first characterized in the bile of the Chinese black bear and is formed by 7b-epimerization of [chenodeoxycholic acid], which is a primary bile acid. … [A256272] UDCA was first approved by the FDA in 1987 for dissolution of gallstones and for primary biliary cirrhosis in 1996.

    Synonyms: Ursodeoxycholic acid, (3α,5β,7β)-3,7-dihydroxycholan-24-oic acidCategories: Bile Acids and Salts, Bile acids and derivatives
  4. Drug

    Mycophenolic acid

    go.drugbank.com/drugs/DB01024
    ApprovedInvestigational

    [A249180] However, mycophenolic acid treatment is more expensive and requires therapeutic drug monitoring to optimize efficacy and minimize toxicity. … [A249180,A249185] Mycophenolic acid is available as enteric-coated tablets of delayed-release, in an effort to improve upper gastrointestinal adverse events by delaying mycophenolic acid release until

    Categories: Mycophenolic Acid and Prodrugs, Antineoplastic and Immunomodulating AgentsSynonyms: Mycophenolic acid, Acido micofenolico
  5. Drug

    Clodronic acid

    go.drugbank.com/drugs/DB00720
    ApprovedInvestigationalVet approved

    Clodronic acid is a first generation bisphosphonate similar to [etidronic acid] and [tiludronic acid]. … [A1923] clodronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and [risedronic acid]

    Categories: Drugs Affecting Bone Structure and Mineralization, clodronic acidSynonyms: Clodronic acid, (dichloromethylene)bisphosphonic acid
  6. Drug

    SP1049C

    go.drugbank.com/drugs/DB04978
    Experimental

    Median survival is encouraging and correlates strongly with dose levels.[A260416] … SP1049C is a novel anthracycline chemotherapeutic agent containing [doxorubicin] and two nonionic pluronic block copolymers.

    Synonyms: doxorubicin with pluronics F-127 and L-61, Doxorubicin HCl with pluronic L-61 and pluronic F-127
  7. Drug

    Selenious acid

    go.drugbank.com/drugs/DB11127
    Approved

    Selenious acid is the acid form of sodium selenite, a form of selenium [L1910]. Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. … It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties.

    Synonyms: Selenous acid, Selenious acidMixtures: Vitamin and Mineral Drink Mix, Multivitamins and Minerals Tablets
  8. Drug

    Lipoic acid

    go.drugbank.com/drugs/DB00166
    ApprovedInvestigationalNutraceutical

    A vitamin-like antioxidant.

    Categories: Enzymes and Coenzymes, Alimentary Tract and MetabolismSynonyms: Lipoic acid, Arlipoic acid
  9. Drug

    Lactic acid

    go.drugbank.com/drugs/DB04398
    ApprovedInvestigationalVet approved

    (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste. … It is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the resulting lactic acid to create a compound having the formula NaC3H5O3.

    Synonyms: Milk acid, Lactic acidMixtures: Lactic Acid 30% / Salicylic Acid 30%, Lactic Acid 10% / Urea 40%
  10. Drug

    Acetic acid

    go.drugbank.com/drugs/DB03166
    ApprovedInvestigational

    Acetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. … (Stedman, 26th ed) Acetic acid otic (for the ear) is an antibiotic that treats infections caused by bacteria or fungus.

    Synonyms: Acetic acid, Ethoic acidMixtures: Hydrocortisone and Acetic Acid, Hydrocortisone and Acetic Acid