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Displaying results 101 - 110 of 136630 in total
  1. Pathway

    Ziconotide NMDA and Substance P Receptor Pain Inhibition Action Pathway

    smpdb.ca/view/SMP0126347
    Drug action

    N-type channel activate lightly myelinated Aδ- and C-fibres, which mediate the release of neurotransmitters substance P, calcitonin gene-related peptide (CGRP), and glutamate. … such as intrathecal morphine and systemic analgesics.

    Drugs: Glutamic acid · Calcium · Sar9, Met (O2)11-Substance P · Ziconotide
  2. Pathway

    Icosapent Prostaglandin G/H synthase 1 and 2 anti-inflammatory Action Pathway

    smpdb.ca/view/SMP0126557
    Drug action

    Icosapent is an important polyunsaturated fatty acid (eicosapentaenoic acid (EPA)). It is mostly found in fish oils. … This molecule also inhibits the arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families because it inhibits the prostaglandin G/H synthase 1 and 2 (COX-1 and COX-2).

    Drugs: Glutathione · Icosapent · Dinoprostone · Calcium · Mesoheme · Prostaglandin G2 +1 more
  3. Pathway

    Cardiolipin Biosynthesis CL(13:0/13:0/13:0/13:0)

    smpdb.ca/view/SMP0225017
    Metabolic

    Sixth, phosphatidylglycerophosphatase and protein-tyrosine phosphatase dephosphorylates PGP to form phosphatidylglycerol (PG). … Cardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition.

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
    Enzymes: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
  4. Pathway

    Cardiolipin Biosynthesis CL(13:0/13:0/13:0/i-13:0)

    smpdb.ca/view/SMP0225036
    Metabolic

    Sixth, phosphatidylglycerophosphatase and protein-tyrosine phosphatase dephosphorylates PGP to form phosphatidylglycerol (PG). … Cardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition.

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
    Enzymes: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
  5. Pathway

    Cardiolipin Biosynthesis CL(13:0/13:0/13:0/a-13:0)

    smpdb.ca/view/SMP0225031
    Metabolic

    Sixth, phosphatidylglycerophosphatase and protein-tyrosine phosphatase dephosphorylates PGP to form phosphatidylglycerol (PG). … Cardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition.

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
    Enzymes: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
  6. Pathway

    Cardiolipin Biosynthesis CL(13:0/13:0/a-13:0/i-13:0)

    smpdb.ca/view/SMP0225255
    Metabolic

    Sixth, phosphatidylglycerophosphatase and protein-tyrosine phosphatase dephosphorylates PGP to form phosphatidylglycerol (PG). … Cardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition.

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
    Enzymes: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
  7. Pathway

    Cardiolipin Biosynthesis CL(13:0/13:0/a-13:0/a-13:0)

    smpdb.ca/view/SMP0225250
    Metabolic

    Sixth, phosphatidylglycerophosphatase and protein-tyrosine phosphatase dephosphorylates PGP to form phosphatidylglycerol (PG). … Cardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition.

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
    Enzymes: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
  8. Pathway

    Cardiolipin Biosynthesis CL(13:0/13:0/i-13:0/i-13:0)

    smpdb.ca/view/SMP0225338
    Metabolic

    Sixth, phosphatidylglycerophosphatase and protein-tyrosine phosphatase dephosphorylates PGP to form phosphatidylglycerol (PG). … Cardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition.

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
    Enzymes: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
  9. Pathway

    Cardiolipin Biosynthesis CL(13:0/i-13:0/i-13:0/i-13:0)

    smpdb.ca/view/SMP0197230
    Metabolic

    Sixth, phosphatidylglycerophosphatase and protein-tyrosine phosphatase dephosphorylates PGP to form phosphatidylglycerol (PG). … Cardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition.

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
    Enzymes: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
  10. Pathway

    Cardiolipin Biosynthesis CL(13:0/a-13:0/a-13:0/i-13:0)

    smpdb.ca/view/SMP0196207
    Metabolic

    Sixth, phosphatidylglycerophosphatase and protein-tyrosine phosphatase dephosphorylates PGP to form phosphatidylglycerol (PG). … Cardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition.

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
    Enzymes: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1