Search

Displaying results 101 - 110 of 161257 in total
  1. Drug

    Nitrazepam

    go.drugbank.com/drugs/DB01595
    Approved

    A benzodiazepine derivative used as an anticonvulsant and hypnotic.

    Synonyms: 1,3-dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepin-2-one, 2,3-dihydro-7-nitro-5-phenyl-1H-1,4-benzodiazepin-2-oneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 Inhibitors
  2. Drug

    Etoricoxib

    go.drugbank.com/drugs/DB01628
    ApprovedInvestigationalWithdrawn

    Etoricoxib is a new COX-2 selective inhibitor. … Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic acid.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine, 5-Chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2,3']bipyridinyl
  3. Drug

    5-methylcytidine 5'-monophosphate

    go.drugbank.com/drugs/DB01995
    Experimental

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-methylcytidine 5'-monophosphate, 5-methylcytidine-5'-monophosphate
  4. Drug

    Desipramine

    go.drugbank.com/drugs/DB01151
    Approved

    TCAs also block histamine-H<sub>1</sub> receptors, &alpha;<sub>1</sub>-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred … See toxicity section below for a complete listing of side effects.

    Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsSynonyms: 5-(γ-methylaminopropyl)iminodibenzyl, 5-(gamma-methylaminopropyl)iminodibenzyl
  5. Drug

    Amitriptyline

    go.drugbank.com/drugs/DB00321
    ApprovedInvestigational

    Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961.

    Synonyms: 5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene, 5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptatrieneMixtures: Apo Peram Tab 3-15, PMS-levazine 3/15 Tab
  6. Drug

    Levomefolic acid

    go.drugbank.com/drugs/DB11256
    Approved

    It is available commercially as a crystalline form of the calcium salt (Metafolin(R)), which has the stability required for use as a supplement [A19276]. … Levomefolate is approved as a food additive and is designated a GRAS (generally regarded as safe) compound [L773].

    Mixtures: FeRiva 21 7, Sodium polysulthionate, 5-methyltetrahydrofolateCategories: Vitamin B Complex, Heterocyclic Compounds, 2-Ring
  7. Drug

    Bimatoprost

    go.drugbank.com/drugs/DB00905
    ApprovedInvestigational

    Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which are synthetic structural analogs of prostaglandin. … [L6910] It was initially approved by the FDA in 2001 for ocular hypertension and later approved for hypothrichosis in 2008, as eyelash growth became a desirable adverse effect for patients using this drug

    Mixtures: BEMATORİN-T 0,3 MG + 5 MG/1 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET, BİMAPRESS DUO 0,3 MG/ML+5 MG/ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  8. Drug

    NITHIAMIDE

    go.drugbank.com/drugs/DB19371
    ApprovedWithdrawn

    Synonyms: 2-acetamido-5-nitrothiazole, N-(5-nitro-2-thiazolyl)acetamideCategories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Hexaminolevulinate

    go.drugbank.com/drugs/DB06261
    ApprovedInvestigational

    C (PDD) System for cystoscopic detection of non-muscle invasive papillary cancer of the bladder for patients suspected or known to have lesion(s) on the basis of a prior cystoscopy. … Hexaminolevulinate is manufactured under the brand Cysview® by Photocure ASA. In Europe, Hexaminolevulinate is marketed under the brand Hexvix®.

    Synonyms: Hexyl 5-amino-4-oxopentanoate hydrochloride, Hexyl(5-amino-4-oxopentanoat)-hydrochloridProducts: Hexvix 85 mg Pulver und Lösungsmittel zur Herstellung einer Lösung zur intravesikalen Anwendung
  10. Drug

    Betrixaban

    go.drugbank.com/drugs/DB12364
    Approved

    Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [A7708]. … VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable death in hospitalized patients [A27287].

    Synonyms: N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, N-(5-chloropyridin-2-yl)-2-[[4-(N,N-dimethylcarbamimidoyl)benzoyl]amino]-5-methoxybenzamideCategories: P-glycoprotein substrates, Heterocyclic Compounds, 1-Ring