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Displaying results 101 - 110 of 35175 in total
  1. Drug

    KAI-1678

    go.drugbank.com/drugs/DB16211
    Investigational

    KAI-1678 is under investigation in clinical trial NCT01106716 (Safety and Efficacy Study of KAI-1678 to Treat Pain in Subjects With Postherpetic Neuralgia).

  2. Drug

    Isoconazole

    go.drugbank.com/drugs/DB08943
    Approved

    Isoconazole is an azole antifungal drug that has similar effectiveness to clotrimazole in the treatment of foot and vaginal infections.

    Categories: combinations of imidazole derivativesProducts: NITRATO DE ISOCONAZOL CREMA1%, ISOCONAZOL CREMA AL 1%
  3. Drug

    KAI-1455

    go.drugbank.com/drugs/DB06064
    Experimental

    In preclinical studies, KAI-1455 showed a dramatic reduction in infarct size when delivered prior to the ischemic insult. … KAI-1455 is a selective epsilon protein kinase C (εPKC) activator designed to reduce ischemic organ injury during procedures where blood supply may be compromised, such as coronary artery bypass grafting

  4. Drug

    Tacrolimus

    go.drugbank.com/drugs/DB00864
    ApprovedInvestigational

    Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. … It was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: Qvaya 1 mg/ml Emulsion zur Anwendung auf der Haut, PROGRAF® XL CAPSULAS DE LIBERACIONPROLONGADA DE 1 MG
  5. Drug

    Moclobemide

    go.drugbank.com/drugs/DB01171
    ApprovedInvestigational

    A reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. … Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (

    Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Monoamine Oxidase A InhibitorsProducts: AURORIX (R) ROCHE TABLETAS LACADAS DE 300 MG, MOCLOBEMID AL 150MG
  6. Drug

    Cefixime

    go.drugbank.com/drugs/DB00671
    ApprovedInvestigational

    [A232920, A232925, A232930] Cefixime is a broad-spectrum antibiotic and an orally-active third-generation semisynthetic cephalosporin. … [A262894,A263011 ,L49293] Cephalosporins are beta-lactam antibiotics and can be used to treat gram-positive and gram-negative bacterial infections which include conditions such as skin infections, resistant

    Mixtures: INNOCEF PLUS 200/125 MG SAŞE, 20 ADET, INNOCEF PLUS 400/125 MG SAŞE, 10 ADETProducts: CEFIXIMA HEXAL AG, CEFIXIM AL 200MG
  7. Drug

    Oxybutynin

    go.drugbank.com/drugs/DB01062
    ApprovedInvestigational

    [A185996,A185999] Oxybutynin, also marketed as Ditropan XL, is an anticholinergic medication used for the relief of overactive bladder symptoms that has been optimized for high levels of safety and … Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients worldwide.

    Products: OXYBUTYNIN AL 5, LYRINELTABLETAS DE 10 MG
  8. Drug

    Alprazolam

    go.drugbank.com/drugs/DB00404
    ApprovedIllicitInvestigational

    [A18125] Alprazolam's adverse effects are generally related to the sedation it can cause. … [A18125] Alprazolam has been mixed with alcohol as a drug of abuse to potentiate the sedative effects of the drug which may lead to coma and death.

    Mixtures: Sentrazolam AMSynonyms: 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine
  9. Drug

    Omeprazole

    go.drugbank.com/drugs/DB00338
    ApprovedInvestigationalVet approved

    Originally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric acid-related disorders. … These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid.

    Mixtures: DOLOTECH TABLETA RECUBIERTA DE LIBERACION RETARDADA, SEVEFIEST TABLETA RECUBIERTA DE LIBERACION RETARDADACategories: Medications that reduce magnesium levels
  10. Drug

    Pentoxifylline

    go.drugbank.com/drugs/DB00806
    ApprovedInvestigational

    [A226410, A226415, A226455] More recently, PTX has been suggested as a possible treatment for COVID-19-induced pulmonary complications due to its ability to regulate the production of inflammatory cytokines … Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties.

    Categories: Compounds used in a research, industrial, or household setting, combinations of xanthinesInternational brands: An Ruo Ning, Ao Le Ni