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Displaying results 101 - 110 of 162531 in total
  1. Drug

    Trifluridine

    go.drugbank.com/drugs/DB00432
    ApprovedInvestigational

    It displays effective antiviral activity against Herpes simplex virus type 1 and 2 [A35271]. … Trifluridine is a fluorinated pyrimidine nucleoside that is structurally related to [idoxuridine] [A35271].

    Mixtures: LONSURF FILM-COATED TABLET 20 MG/8.19 MG, LONSURF FILM-COATED TABLET 20 MG/8.19 MGCategories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Domperidone

    go.drugbank.com/drugs/DB01184
    ApprovedInvestigationalVet approved

    A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.

    Synonyms: 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one, 5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-oneMixtures: LACOMBI 15/10 MG KAPSUL, 28 ADET, DUOLANS 15/30 MG SR KAPSUL, 28 ADET
  3. Drug

    Gimeracil

    go.drugbank.com/drugs/DB09257
    ApprovedInvestigational

    This allows higher concentrations of 5-FU to be achieved with a lower dose of tegafur, thereby also reducing toxic side effects. … The main active ingredient in Teysuno is [DB09256], a pro-drug of [DB00544] (5-FU), which is a cytotoxic anti-metabolite drug that acts on rapidly dividing cancer cells.

    Synonyms: 5-Chloro-4-hydroxy-2-pyridone, 5-Chloro-2,4-dihydroxypyridineMixtures: TS-ONE CAPSULE 25, TS-ONE CAPSULE 25
  4. Drug

    Cimetidine

    go.drugbank.com/drugs/DB00501
    ApprovedInvestigational

    A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. … It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.

    Mixtures: Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17%, Cimetidine 10% / Lidocaine 5% / Salicylic Acid 40%Categories: MATE 2 Inhibitors, MATE 2 Substrates
  5. Drug

    Cefdinir

    go.drugbank.com/drugs/DB00535
    ApprovedInvestigational

    It has been proven to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and skin. … Cefdinir was approved by the FDA in 1997 to treat a variety of mild to moderate infections and was initially marketed by Abbvie.

    Synonyms: (6R,7R,Z)-7-(2-(2-aminothiazol-4-yl)-2-(hydroxyimino)acetamido)-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-hydroxyimino]-acetylamino}-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acidInternational brands: Omnicef R, Xi Fu Ni
  6. Drug

    Lodoxamide

    go.drugbank.com/drugs/DB06794
    Approved

    Lodoxamide is a mast-cell stabilizer for topical administration into the eye.

    Synonyms: N,N'-(2-chloro-5-cyano-m-phenylene)dioxamateProducts: THILOMIDE GÖZ DAMLASI, 5 ML, ALOMİDE % 0.1 GÖZ DAMLASI, ÇÖZELTİ, 5 ML
  7. Drug

    5-fluoro-2'-deoxyuridine-5'-monophosphate

    go.drugbank.com/drugs/DB03761
    Experimental

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-fluoro-2'-deoxyuridine-5'-monophosphate, 5-fluorodeoxyuridine monophosphate
  8. Drug

    Delavirdine

    go.drugbank.com/drugs/DB00705
    ApprovedInvestigationalWithdrawn

    A potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1.

    Synonyms: (N-[2-[4-[3-(1-methylethylamino)pyridin-2-yl]piperazin-1-yl]carbonyl-1H-indol-5-yl] methanesulfonamide), 2-(4-(5-methanesulfonamido-1H-indol-2-ylcarbonyl)-1-piperazinyl)-N-(1-methylethyl)-3-pyridinamineCategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 Substrates
  9. Drug

    Oxybenzone

    go.drugbank.com/drugs/DB01428
    Approved

    It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays. … It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents.

    Synonyms: 2-Benzoyl-5-methoxyphenol, 2-Hydroxy-4-methoxybenzophenoneMixtures: Clé De Peau Beauté 30 Émulsion Protectrice Uv Pour Le Corps, Cyzone Sun By Me
  10. Drug

    Diltiazem

    go.drugbank.com/drugs/DB00343
    ApprovedInvestigational

    Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. … Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class.

    Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein inhibitorsSynonyms: d-cis-diltiazem, (2S-cis)-3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one