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Octinoxate
go.drugbank.com/drugs/DB09496ApprovedInvestigationalIt was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun. … Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage.
Mixtures: A M Stimulus Complex SPF 25, Me Day T9 SPF 25Categories: Compounds used in a research, industrial, or household setting, Protectives Against UV-RadiationDabigatran etexilate
go.drugbank.com/drugs/DB06695ApprovedInvestigational[A177463, A6970, L34675, L34680] Dabigatran etexilate may be used to decrease the risk of venous thromboembolic events in patients in whom anticoagulation therapy is indicated. … [A177463] In contrast to warfarin, because its anticoagulant effects are predictable, lab monitoring is not necessary.[A177463] Dabigatran etexilate was approved by the FDA in 2010.[L6022]
Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein substratesProducts: PRADAXA® 150 MG, Dabahib 75 mg-HartkapselnMenotropins
go.drugbank.com/drugs/DB00032ApprovedInvestigationalIt is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits, alpha = 92 residues, beta=111 residues. … It is used as a fertility medication that is injected either subcutaneously or intramuscularly.
Products: Meriofert 75 I.E. Pulver und Lösungsmittel zur Herstellung einer Injektionslösung, Meriofert PFS 75 I.E. Pulver und Lösungsmittel zur Herstellung einer InjektionslösungRisperidone
go.drugbank.com/drugs/DB00734ApprovedInvestigationalRisperidone is thought to reduce this overactivity through inhibition of dopaminergic D2 receptors and serotonergic 5-HT2A receptors in the brain. … [L12885] Schizophrenia and various mood disorders are thought to be caused by an excess of dopaminergic D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways
International brands: Risperidal M-TabCategories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsRofecoxib
go.drugbank.com/drugs/DB00533ApprovedWithdrawnRofecoxib has a half-life of 17 hours and its mean oral bioavailability at therapeutically recommended doses of 125, 25, and 50 mg is approximately 93%. … The proteins that rofecoxib target include elastin and prostaglandin G/H synthase 2.
Categories: COX-2 Inhibitors, Selective Cyclooxygenase 2 Inhibitors (NSAIDs)Synonyms: 3-phenyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone, 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanoneCetirizine
go.drugbank.com/drugs/DB00341ApprovedInvestigationalThe prevalence of allergic rhinitis in the United States is about 15% according to physician diagnoses, and up to 30%, according to self-reported nasal symptoms. … Allergic rhinitis is associated with multiple missed or unproductive days at work and school, problems with sleep, and other difficulties with day to day activities for many individuals [A175057].
Mixtures: ACERADOX® G, Up and Up all day allergy relief dCategories: P-glycoprotein inhibitors, P-glycoprotein substratesLeuprolide
go.drugbank.com/drugs/DB00007ApprovedInvestigational[A203126, A203132] Leuprolide was first approved in 1985 as a daily subcutaneous injection under the tradename Lupron™ by Abbvie Endocrine Inc. … Prolonged activation of GnRHR results in significant downregulation of sex steroid levels, which is primarily responsible for the clinical efficacy of leuprolide in diverse conditions, including advanced
International brands: Prostap 3Products: ELIGARD ® 45 MG, LUCRIN INJECTION 5 mg/mlOxycodone
go.drugbank.com/drugs/DB00497ApprovedIllicitInvestigationalOxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. … for an extended period.
Mixtures: DEPALGOS® 5 MG /325 MG, Targin 15 mg/7,5 mg RetardtablettenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesIron
go.drugbank.com/drugs/DB01592ApprovedInvestigationalA metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. … Iron is used to build up the blood in anemia.
Mixtures: FENYSOL-Z 40 MG + 15 MG/5 ML ŞURUP, 100 ML, Mega-vim 75 With Beta-carotene - TabletsInternational brands: Ed-In-Sol, Fer-In-SolSitagliptin
go.drugbank.com/drugs/DB01261ApprovedInvestigationalSitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256 … The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255].
Mixtures: สเตกกลูแจน (15 มิลลิกรัม/100 มิลลิกรัม), สเตกกลูแจน (15 มิลลิกรัม/100 มิลลิกรัม)Categories: Drugs Used in Diabetes, Cytochrome P-450 Substrates