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Lacosamide
go.drugbank.com/drugs/DB06218ApprovedInvestigational[A262681] Lacosamide was first approved by the European Commission in August 2008 and was later approved by the FDA in October 2008. … [A262681] It was granted approval by Health Canada in September 2010.[L49206]
Products: APILEP® 100MG, LACOSAMIDA 100MGOfloxacin
go.drugbank.com/drugs/DB01165ApprovedInvestigationalA synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Products: OFLOHEXAL 100MG, OFLOX 100MG BASICSZonisamide
go.drugbank.com/drugs/DB00909ApprovedInvestigationalZonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures. … In 1989, it was approved for commercial use in Japan. The US and Europe approved it in 2000 and 2005, respectively.[A1379,A1383]
Products: ZONEGRAN 100MG, DESIZON 100MGSitagliptin
go.drugbank.com/drugs/DB01261ApprovedInvestigationalSitagliptin was granted FDA approval on October 16, 2006[L6061].
Mixtures: JANUMET XR TABLET 100MG/1000MG, Sidapvia (Dapagliflozin 10mg/Sitagliptin 100mg) Film-Coated TabletProducts: JANUVIA® 100MG, hovid-Sitagliptin Tablet 100mgErtugliflozin
go.drugbank.com/drugs/DB11827ApprovedInvestigational[A31581] Ertugliflozin was first approved by the FDA in December 2017.[A261951, L1132] It was also approved by the European Commission in March 2018.[L48621]
Mixtures: Steglujan (Ertugliflozin 5mg/Sitagliptin 100mg) Film-Coated Tablets, Steglujan (Ertugliflozin 15mg/Sitagliptin 100mg) Film-Coated TabletsProducts: STEGLUJAN FILM-COATED TABLETS 5MG/100MG, STEGLUJAN FILM-COATED TABLETS 15MG/100MGMetformin
go.drugbank.com/drugs/DB00331ApprovedInvestigational[A36559] Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval in the US in 1995.[L12207] … It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels.
Mixtures: JANUMET XR TABLET 100MG/1000MG, XIGDUO XR TABLETS 10MG/1000MGProducts: MET BAY ® 500 TABLETAS RECUBIERTAS, MET BAY ® 850 MG TABLETAS RECUBIERTASErythromycin
go.drugbank.com/drugs/DB00199ApprovedInvestigationalVet approvedIt was originally discovered in 1952.[L5245] Erythromycin is widely used for treating a variety of infections, including those caused by gram-positive and gram-negative bacteria.
Products: Erythromycin Base Base, Erythromycin BaseChlorthalidone
go.drugbank.com/drugs/DB00310ApprovedInvestigationalIn addition to its antihypertensive effects, chlorthalidone has also been shown to decrease platelet aggregation and vascular permeability, as well as promote angiogenesis in vitro, which is thought to … Chlorthalidone has been shown to have a number of pleiotropic effects that differentiate it from other diuretics such as [DB00999].
Mixtures: ATENOCOMP 1A 100MG/25MG, ATENOCOMP 1A 100MG/25MGProducts: Uridon Tab 100mg, Novo-thalidone Tab 100mgMeperidine
go.drugbank.com/drugs/DB00454ApprovedInvestigationalA narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more...
Products: Demerol 10%-liq Im Sc 100mg/ml, DEMOTHINE INJECTION 100MG/2MLHydrochlorothiazide
go.drugbank.com/drugs/DB00999ApprovedInvestigationalVet approved[L7426,L7459] Hydrochlorothiazide was granted FDA approval on 12 February 1959.[L8444]
Mixtures: RAMIPRIL COMP BAS 5/25MG, RAMIPRIL COMP BAS 5/25MGProducts: Hydrodiuril Tab 100mg, Hydrochlorothiazide 100mg Tablets