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Butylscopolamine
go.drugbank.com/drugs/DB09300ApprovedInvestigationalVet approvedIt is also effective at preventing bladder spasms. … Butylscopolamine is a peripherally acting antimuscarinic, anticholinergic agent.
Mixtures: ACETAMINOFÉN 325 MG + N-BUTILBROMURO DE HIOSCINA 10 MG, ACETAMINOFEN 325 MG + BUTIL BROMURO DE HIOSCINA 10 MG TABLETASProducts: N-BUTIL BROMURO DE HIOSCINA 10 MG TABLETAS, N-BUTIL BROMURO DE HIOSCINA 20 MG/MLDarunavir
go.drugbank.com/drugs/DB01264ApprovedInvestigational[L9227] Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19, due to in vitro evidence supporting its ability to combat this infection. … Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as [ritonavir] for the effective management of HIV-1 infection.
Mixtures: REZOLSTA 800 MG/150 MG FİLM KAPLI TABLET, 30 ADET, ZADURNA (Darunavir/Ritonavir Film-coated tablets 400 mg/50 mg)Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsAmantadine
go.drugbank.com/drugs/DB00915ApprovedInvestigationalAn antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. … The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.
Mixtures: BREGAMIN AV, BREGAMIN AVCategories: Influenza A M2 Protein Inhibitor, M2 Protein InhibitorsMannitol
go.drugbank.com/drugs/DB00742ApprovedInvestigationalMannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. … Mannitol may also be used for the promotion of diuresis before irreversible renal failure becomes established; the promotion of urinary excretion of toxic substances; as an Antiglaucoma agent; and as a
Synonyms: D-Mannitol, D-(-)-MannitolInternational brands: Mannisol AMemantine
go.drugbank.com/drugs/DB01043ApprovedInvestigationalInitially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). … In December 2013, the G8 dementia summit concluded that dementia should be considered a global priority with the objective of developing a cure or a disease-modifying therapy by the year 2025 [L5953, F4366
Mixtures: EUTEBROL-DUO, DEMAX 5 MG+10 MG+15 MG+20 MG TEDAVİ BAŞLANGIÇ PAKETİCategories: N-methyl-D-aspartate Receptor Antagonist, Cytochrome P-450 CYP2A6 InhibitorsIbuprofen
go.drugbank.com/drugs/DB01050ApprovedInvestigational[A39076] On the available products, ibuprofen is administered as a racemic mixture. … Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics.
Mixtures: COLDFEN 100 MG+15 MG+1 MG/5 ML ŞURUP, 100 ML, Combogesic 500 mg/150 mg FilmtablettenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesAlprostadil
go.drugbank.com/drugs/DB00770ApprovedInvestigationalThis drug causes vasodilation by directly affecting vascular and ductus arteriosus (DA) smooth muscle, preventing or reversing the functional closure of the DA that occurs shortly after birth. … Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously.
Synonyms: (13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate, 11α,15α-dihydroxy-9-oxo-13-trans-prostenoic acidInternational brands: Caverject DCProcaine
go.drugbank.com/drugs/DB00721ApprovedInvestigationalVet approvedA local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. … Procaine has also been investigated as an oral entry inhibitor in treatment-experienced HIV patients [L1215].
Products: NTCAIN 100 MG/10 ML IM AMPUL, 10 ADET, NTCAIN 100 MG/10 ML IM AMPUL, 100 ADETIrinotecan
go.drugbank.com/drugs/DB00762ApprovedInvestigational[A263381] As an anticancer drug, irinotecan was first commercially available in Japan in 1994 to treat various cancers such as lung, cervical and ovarian cancer. … Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of [camptothecin], which is extracted from the Chinese tree _Camptotheca acuminate_.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic IndexProducts: DARITEX-A, CLORHIDRATO DE IRINOTECAN TRIHIDRATO 20 MG/MLNizatidine
go.drugbank.com/drugs/DB00585ApprovedA histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.
Products: Nu-nizatidine, AXID CAPSULAS 150 MG