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Displaying results 1091 - 1100 of 10000 in total
  1. Drug

    Tixagevimab

    go.drugbank.com/drugs/DB16394
    ApprovedInvestigational

    [A243351, A243361, L39411] Tixagevimab is not approved for any indication by the FDA. … [A243351, A243356, L39411] As the RBD binding site of tixagevimab does not overlap with that of [cilgavimab], the two can be administered to synergistically impair SARS-CoV-2 infection in individuals who

  2. Drug

    Theophylline

    go.drugbank.com/drugs/DB00277
    ApprovedInvestigational

    Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly for asthma, bronchospasm, and COPD. … Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator.

    International brands: Theodur GMixtures: I D M Expectorant Tab, NEO ASMA
  3. Drug

    Floxuridine

    go.drugbank.com/drugs/DB00322
    ApprovedInvestigational

    An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection. Floxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution. … When administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate.

    Synonyms: 1-(2-Deoxy-beta-D-ribofuranosyl)-5-fluorouracil, 1-beta-D-2'-Deoxyribofuranosyl-5-flurouracilCategories: Cytochrome P-450 CYP2C9 Inhibitors, Heterocyclic Compounds, 1-Ring
  4. Target

    NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial

    go.drugbank.com/bio_entities/BE0000243
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Synonyms: Complex I-SGDH
  5. Target

    NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6

    go.drugbank.com/bio_entities/BE0000376
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Synonyms: Complex I-B17
  6. Target

    NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

    go.drugbank.com/bio_entities/BE0000676
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Synonyms: Complex I-ASHI
  7. Target

    Nucleoside 2-deoxyribosyltransferase

    go.drugbank.com/bio_entities/BE0002706
    TargetLactobacillus helveticus

    Synonyms: Nucleoside deoxyribosyltransferase-I
  8. Drug

    Calcium gluconate

    go.drugbank.com/drugs/DB11126
    ApprovedInvestigationalVet approved

    Supplementation may be done to treat or prevent osteoporosis or rickets, consequences of hypocalcemia. It can also be taken by mouth but is not recommended by injection into a muscle. … Each 10 mL of the injection provides 93 mg elemental calcium (Ca++) equivalent to 1 g of calcium gluconate.

    Synonyms: D-gluconic acid, calcium salt (2:1), Calcium di-gluconateMixtures: CAL-EMIL, ELETTROLITICA DI REINTEGRAZIONE CON GLUCOSIO E SODIO GLUCONATO FKI
  9. Drug

    Betamethasone

    go.drugbank.com/drugs/DB00443
    ApprovedInvestigationalVet approved

    [A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. … Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties.

    Synonyms: 9-Fluoro-16β-methylprednisoloneMixtures: Throwers Pbc No. 1, TUDERM-N
  10. Target

    Cytochrome c oxidase subunit 1

    go.drugbank.com/bio_entities/BE0000335
    TargetEnzymeHumans

    Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII...

    Synonyms: Cytochrome c oxidase polypeptide I