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Prophylaxis of Bleeding caused by Hemophilia A
go.drugbank.com/conditions/DBCOND0089517Drugs: Anti-inhibitor coagulant complex · Emicizumab · Fitusiran · Moroctocog alfa · Rurioctocog alfa pegol · Simoctocog alfa +1 moreSynonyms: Prophylaxis of Bleeding caused by Hemophilia APemetrexed
go.drugbank.com/drugs/DB00642ApprovedInvestigationalPemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta. … Its use in non-small cell lung cancer has also been investigated. Pemetrexed was first approved by the FDA in February 4, 2004.[A253907]
Categories: OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index, Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: NEXTREXED 500 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE, PEMETREXED MASTERS® 500 MG POLVO LIOFILIZADO ESTÉRIL PARA RECONSTITUIR A SOLUCION INYECTABLE.Alirocumab
go.drugbank.com/drugs/DB09302ApprovedInvestigationalAlirocumab is a biopharmaceutical that obtained FDA approval in July 2015 as a second line treatment for high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of … It is a human monoclonal antibody part of the family of the PCSK9 inhibitors which are a novel class of anticholesterol therapeutics. From this family, it was the first agent to receive FDA approval.
Categories: Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) InhibitorsProducts: PRALUENT SOLUTION FOR INJECTION IN A PRE-FILLED PEN 75MG/ML, PRALUENT SOLUTION FOR INJECTION IN A PRE-FILLED PEN 150 MG/MLKetoconazole
go.drugbank.com/drugs/DB01026ApprovedInvestigationalKetoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections. … [A188054] At this time it was considered a significant improvement over previous antifungals, [miconazole] and [clotrimazole], due to its broad spectrum and good absorption.
Mixtures: Ketoconazole 2% / Niacinamide 4%, Ketoconazole 2% / Salicylic Acid 2%Categories: P-glycoprotein inhibitors, P-glycoprotein substratesLactose
go.drugbank.com/drugs/DB04465ApprovedInvestigationalWithdrawnA disaccharide of glucose and galactose in human and cow milk. It is used in pharmacy for tablets, in medicine as a nutrient, and in industry.
Mixtures: SERECOR® FORTE DPI 100, SYNTHROID® 112 MCG TABLETASCategories: Compounds used in a research, industrial, or household settingCod liver oil
go.drugbank.com/drugs/DB11321ApprovedNutraceuticalVet approvedAlso being a rich source of vitamin A and D, cod liver oil can be taken orally as daily supplements. … It is used as an adjunct treatment and preventative therapy of rickets, osteomalacia and osteoporosis while meeting the consumption criteria.
Products: Omeza Skin Protectant Gel, ChildLife™ Essentials Cod Liver Oil (Strawberry Flavour)Rhubarb
go.drugbank.com/drugs/DB10651ApprovedRhubarb allergenic extract is used in allergenic testing.
Mixtures: Vita-lax, Lax-easeProducts: Lax Special Tab 575mgAmoxicillin
go.drugbank.com/drugs/DB01060ApprovedInvestigationalVet approvedAmoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972.
Mixtures: AMOXICILLINA E ACIDO CLAVULANICO SANDOZ A/S, AMOXICILLINA E ACIDO CLAVULANICO SANDOZ A/SCategories: Penicillin G, Heterocyclic Compounds, 1-RingDiltiazem
go.drugbank.com/drugs/DB00343ApprovedInvestigationalApproved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. … Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: (+)-cis-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate ester, (2S,3S)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetateTasimelteon
go.drugbank.com/drugs/DB09071ApprovedInvestigationalIn blind individuals, a lack of light stimulation causes an extension of the 24-hour circadian cycle and can lead to progressively delayed sleep onset. … Tasimelteon is a selective dual melatonin receptor agonist indicated for the treatment of Non-24-Hour Sleep-Wake Disorder (N24HSWD).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: N-{[(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cyclopropyl]methyl}propanamide