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Bimatoprost
go.drugbank.com/drugs/DB00905ApprovedInvestigationalBimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form. … [L6910] It was initially approved by the FDA in 2001 for ocular hypertension and later approved for hypothrichosis in 2008, as eyelash growth became a desirable adverse effect for patients using this drug
Synonyms: (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamideMixtures: GANFORT® UD SOLUCION OFTALMICA, BimatoTim-Vision sine 0,3 mg/ml + 5 mg/ml Augentropfen, Lösung im EinzeldosisbehältnisEtidronic acid
go.drugbank.com/drugs/DB01077ApprovedInvestigationalEtidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid]. … [A1923] Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and [risedronic acid]
Mixtures: Mylan-eti-cal CarepacCategories: etidronic acid and calcium, sequential, Drugs Affecting Bone Structure and MineralizationMethoxamine
go.drugbank.com/drugs/DB00723ApprovedInvestigationalWithdrawnAn alpha-adrenergic agonist that causes prolonged peripheral vasoconstriction. It has little if any direct effect on the central nervous system.
Categories: Adrenergic and Dopaminergic AgentsProducts: Vasoxyl Inj 20mg/mlFormoterol
go.drugbank.com/drugs/DB00983ApprovedInvestigationalFormoterol is an inhaled beta<sub>2</sub>-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. … [L11256] It is available as a single-entity product [L10986,L11223] and in several formulations in combination with both inhaled corticosteroids [L10995,L10619] and long-acting muscarinic antagonists.
Mixtures: FOSTER NEXTHALER 100UG/6UG, FOSTER NEXTHALER 100UG/6UGCategories: formoterol and mometasone, formoterol and budesonideGlipizide
go.drugbank.com/drugs/DB01067ApprovedInvestigational[A179485] Glipizide was first approved by the FDA in 1994 and is available in extended-release tablets under the brand name Glucotrol®, as well as in combination with metformin under the brand name Metaglip … Glipizide is an oral hypoglycemic agent in the second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 diabetes mellitus.
Synonyms: N-{4-[β-(5-methylpyrazine-2-carboxamido)ethyl]benzenesulphonyl}-N'-cyclohexylureaMixtures: Glipizide and Metformin HCl, Glipizide and Metformin HClUrsodeoxycholic acid
go.drugbank.com/drugs/DB01586ApprovedInvestigational[A256272] UDCA was first approved by the FDA in 1987 for dissolution of gallstones and for primary biliary cirrhosis in 1996. … [A256267,A256463] UDCA was first characterized in the bile of the Chinese black bear and is formed by 7b-epimerization of [chenodeoxycholic acid], which is a primary bile acid.
Categories: Bile Acids and Salts, Bile and Liver TherapyProducts: URSOFALK 500MG FILMTABL, TILLHEPO 500MG HARTKAPSELCinnarizine
go.drugbank.com/drugs/DB00568ApprovedInvestigationalFirst synthesized by Janssen Pharmaceuticals in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and motion sickness. … Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system to interfere with the signal transmission between vestibular apparatus of the inner ear and the vomiting
Categories: Calcium-Regulating Hormones and AgentsProducts: CN - 25, PRINAZIN TABLET 25MGTerbinafine
go.drugbank.com/drugs/DB00857ApprovedInvestigationalVet approved[A1279] Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell wall … Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues.
Synonyms: (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine, (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamineMixtures: Terbinafine HCl Chlortimazole and TolnaftateAstemizole
go.drugbank.com/drugs/DB00637ApprovedWithdrawnIt was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice. … Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms.
Products: Hismanal Tab 10mg, Hismanal - Tab 10mgCamponotus pennsylvanicus
go.drugbank.com/drugs/DB14710ApprovedCamponotus pennsylvanicus allergenic extract is used in allergenic testing.
Synonyms: Black carpenter ant, Black carpenter ant wholeProducts: Black Carpenter Ant