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Erenumab
go.drugbank.com/drugs/DB14039ApprovedInvestigationalErenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines … CGRP receptor, which is believed to play a critical role in migraine [L2823].
Products: PASURTA® 140 MG /ML, Pasurta 70mg/ml Solution for Injection in a Prefilled SyringePosaconazole
go.drugbank.com/drugs/DB01263ApprovedInvestigationalVet approvedPosaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Posaconazol 1A Pharma 100 mg - magensaftresistente Tabletten, POSIOLE® IV SOLUCIÓN PARA INFUSIÓN 300 MG/16.7 MLMethylprednisolone hemisuccinate
go.drugbank.com/drugs/DB14644ApprovedInvestigationalA water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP3A InducersProducts: A-methapred, SOLU- MEDROL (R)500 MGRitonavir
go.drugbank.com/drugs/DB00503ApprovedInvestigationalIt is now more commonly used as a booster of other protease inhibitors and is available in both liquid formulations and as capsules. … While ritonavir is not an active antiviral agent against hepatitis C virus (HCV) infection, it is added in combination therapies indicated for the treatment of HCV infections as a booster.
Mixtures: RITOPIN® 100 MG + 25 MG TABLETA RECUBIERTA., ALUVIA (100 MG/25 MG)Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsAbacavir
go.drugbank.com/drugs/DB01048ApprovedInvestigationalAbacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. … Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring.
Mixtures: ABACAVIR 600 MG Y LAMIVUDINA 300 MG, N/ACategories: Heterocyclic Compounds, 2-RingChlorhexidine
go.drugbank.com/drugs/DB00878ApprovedInvestigationalVet approvedWithdrawn[A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two biguanide groups joined by a central hexamethylene chain. … Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms.
Synonyms: N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide, 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide)International brands: Prevacare RAvanafil
go.drugbank.com/drugs/DB06237ApprovedAvanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. … In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both [sildenafil] and [vardenafil] but less selectivity than [tadalafil], suggesting a relatively
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesSynonyms: (S)-4-(3-Chloro-4-methoxybenzylamino)-2-(2-hydroxymethylpyrrolidin-1-yl)-N-pyrimidin-2-ylmethyl-5-pyrimidinecarboxamideCiclopirox
go.drugbank.com/drugs/DB01188ApprovedInvestigationalCiclopirox olamine (used in preparations called Batrafen, Loprox, Mycoster, Penlac and Stieprox) is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses.
Mixtures: Ciclopirox 3% / Itraconazole 5% / Urea 20%, Ciclopirox 8% / Fluconazole 1% / Terbinafine HCl 1%Categories: Heterocyclic Compounds, 1-RingCefalotin
go.drugbank.com/drugs/DB00456ApprovedVet approvedWithdrawnCefalotin is a cephalosporin antibiotic.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid, 7-(Thiophene-2-acetamido)cephalosporinCarmustine
go.drugbank.com/drugs/DB00262ApprovedInvestigationalA cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: N,N'-Bis(2-chloroethyl)-N-nitrosourea