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Idebenone

It is not currently approved for use by either the Food and Drug Administration (USA) or Health Canada. … LHON is a mitochondrially inherited degeneration of retinal ganglion cells, resulting in acute central vision loss.

Atenolol

Atenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. … Atenolol itself was developed early on in this history by Alvogen Malta under the trade name Tenormin and received FDA approval in September, 1981.

Pyrophosphoric acid

Patiromer

Patiromer is a powder for suspension in water for oral administration, approved in the U.S. as Veltassa in October, 2015. … Patiromer sorbitex calcium is an amorphous, free-flowing powder that is composed of individual spherical beads.

Melatonin

Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. … In mammals, melatonin is produced by the pineal gland.

Temoporfin

It was first authorized for market by the European Medicines Agency in October 2001. It is currently available under the brand name Foscan. … Temoporfin is a photosensitizing agent used in the treatment of squamous cell carcinoma of the head and neck [FDA Label].

Finasteride

It works in a similar fashion as [dutasteride], which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. … [L6244,L10565] In 1998, it was approved by the FDA to treat male pattern hair loss.

Fomivirsen

It is an antiviral agent that was used in the treatment of cytomegalovirus retinitis (CMV) in immunocompromised patients, including those with AIDS. … Fomivirsen is a antisense 21 mer phosphorothioate oligonucleotide.

Hydroxypropyl cellulose

Lacrisertis a formulation of hydroxypropyl cellulose that is used for artificial tears. … It is used to treat syndromes characterized by insufficient tear production (keratoconjunctivitis sicca), recurrent corneal erosions, decreased corneal sensitivity, exposure and neuroparalytic keratitis

Bisoprolol

[A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and is a useful alternative to non-selective β-blocker drugs in the treatment of hypertension such … It may be used alone or in combination with other drugs to manage hypertension[L7219] and can be useful in patients with chronic obstructive pulmonary disease (COPD) due to its receptor selectivity.