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Somatostatin
go.drugbank.com/drugs/DB09099ApprovedInvestigationalWithdrawnProsomastatin is further process into two active forms, somatostatin-14 (SST-14) and somatostatin-28 (SST-28), an extended SST-14 sequence to the N-terminus [A20384]. … Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues [T28] that regulates the endocrine system.
Synonyms: Synthetic somatostatin-14Products: SOMATOSTATIN EUMEDICA 250 MCG IV INFÜZYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET, SOMATOSAN 3 MG IV INFUZYON ICIN 1 AMPULPrucalopride
go.drugbank.com/drugs/DB06480ApprovedInvestigational[A40254] Prucalopride was developed by Shire Development LLC and approved for use in Europe in 2009,[A40250] in Canada on December 7, 2011 and by the FDA on December 17, 2018.[L4880] … [A37348] The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies.
Categories: Heterocyclic Compounds, 2-RingProducts: Resolor Film-coated Tablet 2 mg, Resolor Film-coated Tablet 1 mgCalcitriol
go.drugbank.com/drugs/DB00136ApprovedInvestigationalNutraceuticalCalcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D<sub>3</sub>, 1,25-dihydroxyvitamin … [DB00146] undergoes hydroxylation to form calcitriol via 1α-hydroxylase (CYP27B1) activity [A26353]. Calcitriol is considered to be the most potent metabolite of vitamin D in humans [A3366].
Synonyms: 1α,25(OH)2D3, 1α,25-dihydroxyvitamin D3Products: CALCIJEX 1 MCG/ML IV AMPUL, 25 ADET, TEORY 1 MCG/ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 25 ADETPembrolizumab
go.drugbank.com/drugs/DB09037ApprovedInvestigational[A18829] It contains 32 cysteine residues and the complete folded molecule includes 4 disulfide linkages as interchain bonds and 23 interchain bonds. … It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation.
Categories: PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsProducts: KEYTRUDA® 100 MG, KEYTRUDA 100 MG/4 ML IV INFUZYONLUK COZELTI İÇEREN FLAKON, 1 ADETHydroxyurea
go.drugbank.com/drugs/DB01005ApprovedInvestigationalHydroxyurea is a non-alkylating antineoplastic agent that was first synthesized in 1869 but was not characterized biologically until 1928. … [A262596] It was first approved by the FDA in 1998 for the treatment of sickle cell anemia in adults.
Products: Hydroxycarbamid 1A Pharma 100 mg - Filmtabletten, SIKLOS® 100 MG COMPRIMIDOSPerampanel
go.drugbank.com/drugs/DB08883ApprovedInvestigationalIt is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 3-(2-Cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-oneRasagiline
go.drugbank.com/drugs/DB01367ApprovedInvestigationalRasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
Synonyms: (R)-N-2-Propynyl-1-indanamine, (R)-indan-1-yl-prop-2-ynyl-amineProducts: RASALAS 1 MG TABLET, 60 ADET, RASALAS 1 MG TABLET, 90 ADETEletriptan
go.drugbank.com/drugs/DB00216ApprovedInvestigationalEletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine headaches.
Categories: Heterocyclic Compounds, 2-Ring, Serotonin-1b and Serotonin-1d Receptor AgonistProducts: Eletop 20 mg-Filmtabletten, Relpax 20 mg - FilmtablettenHistamine
go.drugbank.com/drugs/DB05381ApprovedInvestigationalA depressor amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
Mixtures: Histamine DHCl 0.10 Percent and Menthol 2 Percent, Md Science CannabidiolCategories: Heterocyclic Compounds, 1-RingGlyburide
go.drugbank.com/drugs/DB01016ApprovedInvestigational[A183617] Glyburide was granted FDA approval on 1 May 1984.[L8117] A formulation with metformin was granted FDA approval on on 31 July 2000.[L8120]
Mixtures: DUPLAX 250 MG/1.25 MG FILM KAPLI TABLET, 120 ADET, DUPLAX 250 MG/1.25 MG FILM KAPLI TABLET, 180 ADETSynonyms: 1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea, 1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea