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Displaying results 1091 - 1100 of 10000 in total
  1. Drug

    Sunvozertinib

    go.drugbank.com/drugs/DB18925
    Investigational

    [A274143] Sunvozertinib was granted accelerated approval in the US on July 2, 2025 for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor … [L53488] EGFR is a transmembrane protein with cytoplasmic kinase activity commonly expressed by non-small cell lung carcinomas (NSCLCs).

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: 2-Propenamide, N-[5-[[4-[[5-chloro-4-fluoro-2-(1-hydroxy-1- methylethyl)phenyl]amino]-2-pyrimidinyl]amino]-2-[(3R)-3-(dimethylamino)-1-pyrrolidinyl]-4-methoxyphenyl]-, N-{5-[(4-{[5-chloro-4-fluoro-2-(1-hydroxy-1-methylethyl)phenyl]amino}pyrimidin-2-yl)amino]-2-[(3R)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl}prop-2-enamide
  2. Drug

    Ethyl (4R)-4-{[(2R,5S)-2-(4-fluorobenzyl)-6-methyl-5-{[(5-methyl-1,2-oxazol-3-yl)carbonyl]amino}-4-oxoheptanoyl]amino}-5-[(3S)-2-oxo-3-pyrrolidinyl]pentanoate

    go.drugbank.com/drugs/DB02313
    Experimental

    Synonyms: Ethyl (4R)-4-{[(2R,5S)-2-(4-fluorobenzyl)-6-methyl-5-{[(5-methyl-1,2-oxazol-3-yl)carbonyl]amino}-4-oxoheptanoyl]amino}-5-[(3S)-2-oxo-3-pyrrolidinyl]pentanoate
  3. Drug

    Ferrous gluconate

    go.drugbank.com/drugs/DB14488
    ApprovedInvestigational

    Mixtures: Vitamine Du Groupe B Plus Fer - Liq, Supplement De FerSynonyms: D-gluconic acid, iron(2+) salt (2:1), Iron(2+) gluconate (1:2)
  4. Drug

    Oxfendazole

    go.drugbank.com/drugs/DB11446
    InvestigationalVet approved

    Oxfendazole is a sulfoxide metabolite of fenbendazole. This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 5-phenylsulfinyl-2-carbomethoxyaminobenzimidazole, 5-(phenylsulfinyl)-2-benzimidazolecarbamic acid methyl ester
  5. Drug

    Mirdametinib

    go.drugbank.com/drugs/DB07101
    ApprovedInvestigational

    [A265065] Mirdametinib selectively and potently inhibits the MEK1/2 enzymes.[A265065] … Mirdametinib is a mitogen-activated protein kinase (MAP2K, MEK, MAPKK) inhibitor. On February 11, 2025, mirdametinib was approved by the FDA for the treatment of neurofibromatosis type 1 (NF1).

    Categories: P-glycoprotein substratesSynonyms: N-(((R)-2,3-DIHYDROXYPROPYL)OXY)-3,4-DIFLUORO-2-((2-FLUORO-4-IODOPHENYL)AMINO)BENZAMIDE N-((2R)-2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-(2-FLUORO-4-IODOANILINO)BENZAMIDE, (-)-N-(((R)-2,3-DIHYDROXYPROPYL)OXY)-3,4-DIFLUORO-2-((2-FLUORO-4-IODOPHENYL)AMINO)BENZAMIDE
  6. Drug

    HUB-101

    go.drugbank.com/drugs/DB18656
    Experimental

    Synonyms: Adeno-associated viral 2/5 (AAV2/5) vector expressing the human KCNJ13 gene
  7. Drug

    Bufotenine

    go.drugbank.com/drugs/DB01445
    ExperimentalIllicit

    Bufotenin has been used as a tool in CNS studies and misused as a psychedelic. … A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics.

    Synonyms: 3-[2-(dimethylamino)ethyl]-5-indolol, 3-[2-(dimethylamino)ethyl]indol-5-olCategories: Heterocyclic Compounds, 2-Ring, Serotonin 5-HT1 Receptor Antagonists
  8. Drug

    Adenosine 3',5'-diphosphate

    go.drugbank.com/drugs/DB01812
    Experimental

    Synonyms: 3',5'-ADP, 3'-Phosphoadenosine 5'-phosphateCategories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Stavudine triphosphate

    go.drugbank.com/drugs/DB02887
    Experimental

    Synonyms: 2',3'-Dideoxy-2',3'-dehydrothymidine 5'-triphosphateCategories: Heterocyclic Compounds, 1-Ring
  10. Drug

    (2S)-1-{[5-(1H-Indazol-5-yl)-3-pyridinyl]oxy}-3-(7aH-indol-3-yl)-2-propanamine

    go.drugbank.com/drugs/DB06977
    Experimental

    Synonyms: (2S)-1-{[5-(1H-Indazol-5-yl)-3-pyridinyl]oxy}-3-(7aH-indol-3-yl)-2-propanamine