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Displaying results 1101 - 1110 of 10000 in total
  1. Pathway

    Indacaterol Action Pathway

    smpdb.ca/view/SMP0126090
    Drug action

    Indacaterol is an inhaled beta-2 adrenergic agonist that is both rapid onset and long acting. The purpose of this drug is to relax bronchial smooth muscle to help treat COPD, asthma, and chronic bronchitis by opening the airways. It can ...

    Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Indacaterol
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  2. Pathway

    Levosalbutamol Action Pathway

    smpdb.ca/view/SMP0126092
    Drug action

    Levosalbutamol is a beta-2 adrenergic receptor agonist that is used to treat COPD and asthma. It is a short acting drug that can be found under the brand name Xopenex. Levosalbutamol is inhaled, and works by relaxing the smooth muscle in...

    Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Levosalbutamol
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  3. Pathway

    Clenbuterol Action Pathway

    smpdb.ca/view/SMP0126097
    Drug action

    Clenbuterol is a beta-2 adrenergic agonist used as a bronchodilator. This drug is taken orally and is used for the treatment of asthma, bronchitis, and COPD. It exerts its effect through activation of adenylyl cyclase leading to muscle r...

    Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Clenbuterol · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  4. Pathway

    Isoetharine Action Pathway

    smpdb.ca/view/SMP0126101
    Drug action

    Isoetharine is a selective beta-2 adrenergic agonist used as a bronchodilator. This is a fast acting drug offering relief of bronchospasm for the treatment of emphysema, bronchitis, and asthma. Isoetharine is inhaled and acts by activati...

    Drugs: ATP · Isoetharine · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  5. Pathway

    Vilanterol Action Pathway

    smpdb.ca/view/SMP0126103
    Drug action

    Vilanterol is a long acting beta-2 adrenergic agonist. It can be found under the brand names Anoro, Anoro Ellipta, Breo Ellipta, and Trelegy Ellipta. It has a 24 hour activity and is used as a bronchodilator for the treatment of COPD and...

    Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Vilanterol
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  6. Pathway

    Vibegron Action Pathway

    smpdb.ca/view/SMP0126109
    Drug action

    Vibegron is a beta-3 adrenergic agonist the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency in adults. It can be found under the brand name Gemtesa and it relaxes the detru...

    Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Vibegron
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  7. Pathway

    Ephedrine B2-Adrenergic Bronchodilation Action Pathway

    smpdb.ca/view/SMP0126111
    Drug action

    Ephedrine is an alpha and beta-adrenergic agonist indicated to treat hypotension under anesthesia, allergic conditions, bronchial asthma, and nasal congestion. It is administered as an intravenous injection, and can be found under the br...

    Drugs: ATP · Potassium cation · Ephedrine · Calcium · Magnesium cation · Cyclic adenosine monophosphate
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
  8. Drug

    Mifamurtide

    go.drugbank.com/drugs/DB13615
    ApprovedInvestigational

    In a large, randomized, open-label, multicenter, phase III trial, the treatment of mifamurtide in conjunction with three- or four-drug combination chemotherapy (doxorubicin, cisplatin, and high-dose methotrexate … Also called L-MTP-PE, mifamurtide may be a liposomal form of of the active ingredient MTP-PE, which is a synthetic, less pyrogenic, and longer-acting derivative of muramyl dipeptide (MDP).

    Products: MEPACT 4 MG INFÜZYONLUK DISPERSIYON KONSANTRESI IÇIN TOZ ,FLAKON, 1 ADET, MEPACT® POLVO PARA CONCENTRADO PARA DISPERSIÓN PARA PERFUSIÓN
  9. Drug

    Sufentanil

    go.drugbank.com/drugs/DB00708
    ApprovedInvestigational

    Sufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. … Also known as _Dsuvia_, the sublingual form is used for the management of acute pain in adults that is severe to warrant the use of an opioid analgesic in certified medically supervised healthcare settings

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 舒芬太尼, N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-N-phenylpropanamide
  10. Drug

    Tezacaftor

    go.drugbank.com/drugs/DB11712
    ApprovedInvestigational

    Tezacaftor is a drug of the cystic fibrosis transmembrane conductance regulator (CFTR) corrector class. … [A20298,A20299] As a result, CF patients produce thick, sticky mucus that clogs the ducts of organs where it is produced making patients more susceptible to complications such as infections, lung damage

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates