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Pentoxifylline
go.drugbank.com/drugs/DB00806ApprovedInvestigational[A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated for … [A226410, A226415, A226455] More recently, PTX has been suggested as a possible treatment for COVID-19-induced pulmonary complications due to its ability to regulate the production of inflammatory cytokines
Categories: Compounds used in a research, industrial, or household setting, Drugs for Obstructive Airway DiseasesInternational brands: Ao Le NiCollagenase clostridium histolyticum
go.drugbank.com/drugs/DB00048ApprovedInvestigational[L14912] On July 6, 2020 a combination of injectable bacterial collagenases was approved by the FDA for the treatment of cellulite in adult women. … [L14882] The topical formulation is used for the debridement of necrotic tissue due to burns or chronic ulcers.
Categories: Preparations for Treatment of Wounds and UlcersSynonyms: Clostridiopeptidase AAclidinium
go.drugbank.com/drugs/DB08897ApprovedAclidinium is an anticholinergic for the long-term management of chronic obstructive pulmonary disease (COPD). … It has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. FDA approved on July 24, 2012.
Categories: Drugs for Obstructive Airway DiseasesPrademagene zamikeracel
go.drugbank.com/drugs/DB17895ApprovedInvestigational[L53008] COL7A1 encodes type VII collagen (C7), which is a major component of anchoring fibrils (AF) that are critical for dermal-epidermal cohesion. … [L53008] Prademagene zamikeracel was first approved by the FDA on April 29, 2025, for the treatment of recessive dystrophic epidermolysis bullosa (RDEB), a skin disorder associated with excessive blistering
Foreskin keratinocyte (neonatal)
go.drugbank.com/drugs/DB10772ApprovedIt is used for grafting onto partial-thickness wounds, where it offers a favorable matrix for host cell migration [L2452]. … A gel made of bovine collagen is used as the matrix for cell growth and differentiation.
Cabotegravir
go.drugbank.com/drugs/DB11751ApprovedInvestigational[L31198] While previously administered once monthly only, this combination product was granted FDA approval for dosing every two months on February 01, 2022 [L40084] and without the need for an oral lead-in … Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside reverse transcriptase inhibitor, [rilpivirine].
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseProducts: Apretude 600mg Prolonged-release suspension for injectionFlurpiridaz F-18
go.drugbank.com/drugs/DB18773ApprovedFlurpiridaz F-18 is a radioactive diagnostic drug indicated for positron emission tomography (PET) myocardial perfusion imaging (MPI), which is an imaging process used in patients with known or suspected … [A264519] Flurpiridaz F-18 is an analog of pyridaben, a mitochondrial complex 1 (MC-1) inhibitor.[L51659]
Nogapendekin alfa
go.drugbank.com/drugs/DB18740ApprovedInvestigationalBCG) immunotherapy; however, NMIBC is associated with a risk of disease recurrence or progression into advanced disease despite initial treatment with BCG. … Nogapendekin alfa is a human IL-15N72D variant.
Selegiline
go.drugbank.com/drugs/DB01037ApprovedInvestigationalVet approvedA selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. … It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability.
Synonyms: L-DeprenalinCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Compounds used in a research, industrial, or household setting